Gene Genealogies, Variation and Evolution: A Primer in Coalescent Theory - Softcover

Hein, Jotun; Schierup, Mikkel H.; Wiuf, Carsten

Softcover

ISBN 10: 0198529961 ISBN 13: 9780198529965

Publisher: Oxford University Press, 2005

Synopsis

Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of DNA sequences. The completion of the sequencing of the human genome and accompanying determination of SNPs and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.

About this title

About the Author

Jotun Hein is a Professor of Bioinformatics Department of Statistics, University of Oxford. Mikkel Schierup and Carsten Wiuf are both at the Bioinformatics Research Center, University of Aarhus, Denmark.

Edition details

• Publisher: Oxford University Press
• Publication date: 2005
• Language: English
• ISBN 10: 0198529961
• ISBN 13: 9780198529965
• Binding: Paperback
• Edition number: 1
• Number of pages: 296