Organic Synthesis (Oxford Chemistry Primers)

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9780198557913: Organic Synthesis (Oxford Chemistry Primers)

This practical book uses a wide range of examples in a versatile approach to the design of effective syntheses. Retrosynthetic analysis--a method of identifying simple starting materials for a synthesis--is introduced with emphasis on the importance of bond polarity and functional group interconversions. The next section discusses how an effective route to a target molecule containing more than one functional group can be followed, while later chapters review methods for the control of chemo-, regio-, and stereoselectivity, and include a discussion of protecting groups. Finally, four syntheses of pyrrolidine alkaloids are compared using previously described principles.

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From the Back Cover:

This series of short texts provides accessible accounts of a range of essential topics in chemistry. Written with the needs of the student in mind, the Oxford Chemistry Primers offer just the right level of detail for undergraduate study, and will be invaluable as a source of material commonly presented in lecture courses yet not adequately covered in existing texts. All the basic principles and facts in a particular area are presented in a clear and straightforward style, to produce concise yet comprehensive accounts of topics covered in both core and specialist courses. This book introduces a logical approach for the design of synthetic routes to reasonably complex organic molecules from simple starting materials. It describes the concept of 'retrosynthesis', which allows suitable simple starting materials to be identified; the importance of bond polarity and functional group interconversions; how to find an effective route to a target molecule containing more than one functional group; and valuable strategies to adopt when designing syntheses. The text also includes a review of methods for the control of chemo-, regio-, and stereoselectivity, and a discussion of protecting groups. Finally four syntheses of the pyrrolidine alkaloids are compared and contrasted using the principles described in the book. Practice examples are provided throughout the book.

About the Author:

Chris Willis and Martin Wills are both at the University of Bath.

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Book Description Oxford University Press, United Kingdom, 1996. Paperback. Book Condition: New. Language: English . Brand New Book. The ability to design effective syntheses is an essential skill for organic chemists. This valuable text uses a wide range of examples to teach students of chemistry how to adopt a logical and versatile approach to the design of synthetic routes. The concept of retrosynthetic analysis - a means for identifying simple starting materials for a synthesis - is first introduced with emphasis on the importance of bond polarity and functional group interconversions. The next section describes how an effective route to a target molecule containing more than one functional group can be elucidated, and gives useful strategies to adopt when designing syntheses. Later chapters review methods for the control of chemo-, regio-, and stereoselectivity, and include a discussion of protecting groups. Finally, four syntheses of the pyrrolidine alkaloids are compared and contrasted using the principles described in the book. Practice examples are provided throughout, making this concise text an invaluable study aid for all undergraduate chemists. Bookseller Inventory # AOP9780198557913

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