An account of the medical sleuthing that led to the discovery of Lyme disease. It not only tells the history of the discovery of Lyme disease over centuries and continents but also provides information about the disease and its treatment. In the process it offers details about the medical process: how physicians make a diagnosis, how they test its accuracy, and how scientific inquiry is influenced by its cultural context. Dr Jonathan Edlow begins his detective story in Lyme, Connecticut, with the accounts of two housewives who in the mid-1970s noticed a baffling array of symptoms afflicting members of their families and others in the community. As physicians studied this strange disease, they were led to reports of similar symptoms in other eras and countries. Edlow chronicles how connections were ultimately established between symptoms and tick bites, leading to the discovery of the stages of the disease, its specific microbial cause, and its treatment. He brings the story into the 21st century by discussing legal and legislative issues as well as factors that have led to recent widespread outbreaks of Lyme disease and to the controversies over its diagnosis, vaccine, treatment and even its very definition.
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"Bull's-Eye is a compelling mystery and a riveting account of science in action."-Robert B. Parker; "A valuable guide for dealing with emerging diseases. . . . The best thing of all about Bull's-Eye is that it lays out the unknowns along with the knowns, the mainstream view along with alternative readings, and thus reveals science for what it is: a perpetual, and admirable, work in progress."-Andrew C. Revkin, New York Times Book Review; "The story of an emerging infection and its history . . . beautifully written. . . . Anyone who is curious about Lyme disease or medical discovery in general will find this book interesting reading."-Raymond Dattwyler, New England Journal of MedicineAbout the Author:
Jonathan A. Edlow is vice chairman of the department of emergency medicine at the Beth Israel Deaconess Medical Center and assistant professor of medicine at the Harvard Medical School. He frequently lectures on Lyme disease and has written many medical detective stories that have appeared in the pages of Boston Magazine and Ladies' Home Journal.
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