Madness and Memory: The Discovery of Prions--A New Biological Principle of Disease

4.06 avg rating
( 99 ratings by Goodreads )
 
9780300216905: Madness and Memory: The Discovery of Prions--A New Biological Principle of Disease
View all copies of this ISBN edition:
 
 

A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases

In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate. His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.
 
In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

"synopsis" may belong to another edition of this title.

About the Author:

Stanley B. Prusiner, M.D., is director of the Institute for Neurodegenerative Diseases and professor of neurology at the University of California, San Francisco. The recipient of an array of scientific honors, he was awarded the Nobel Prize in Physiology or Medicine in 1997. He lives in San Francisco.

Review:

Madness and Memory is the story of one of the most important discoveries in recent medical history, and it is also a vivid and compelling portrait of a life in science.”—Oliver Sacks (Oliver Sacks 2013-10-11)

"Perhaps not since James D. Watson’s 1968 memoir The Double Helix has the down and dirty business of world-class science been given such an airing . . . We are free to enjoy the spectacle of top gladiators at work in an utterly fascinating arena."—Abigail Zuger, M.D., New York Times (Abigail Zuger, M.D. New York Times)

“. . . the story hinges on Prusiner’s discovery of prions, ‘a new biological principle of disease’. It is a remarkable tale . . . [a] testament to the staggering intellect and courage involved in one of the most exciting discoveries since the DNA double helix.”—Giovanna Mallucci, Nature (Giovanna Mallucci Nature)

"About this title" may belong to another edition of this title.

Other Popular Editions of the Same Title

9780300191141: Madness and Memory: The Discovery of Prions--A New Biological Principle of Disease

Featured Edition

ISBN 10: 0300191146 ISBN 13: 9780300191141
Publisher: Yale University Press, 2014
Hardcover

Top Search Results from the AbeBooks Marketplace

Stock Image

1.

Stanley B. Prusiner
Published by Yale.
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Softcover Quantity Available: 3
Seller:

Book Description Yale. Condition: New. Fine. Paperback. 2014. Originally published at $22. Seller Inventory # W101262b

More information about this seller | Contact this seller

Buy New
US$ 5.50
Convert currency

Add to Basket

Shipping: US$ 4.00
Within U.S.A.
Destination, rates & speeds
Stock Image

2.

Prusiner, Stanley B.
Published by Yale University Press (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 2
Seller:
Book Deals
(Lewiston, NY, U.S.A.)

Book Description Yale University Press, 2016. Paperback. Condition: BRAND NEW. Seller Inventory # 0300216904_abe_bn

More information about this seller | Contact this seller

Buy New
US$ 13.74
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds
Seller Image

3.

Prusiner, Stanley B.
Published by Yale University Press (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 20
Seller:
booksXpress
(Freehold, NJ, U.S.A.)

Book Description Yale University Press, 2016. Paperback. Condition: new. Seller Inventory # 9780300216905

More information about this seller | Contact this seller

Buy New
US$ 15.86
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds
Stock Image

4.

Stanley B. Prusiner
Published by Yale University Press, United States (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 10
Seller:
Book Depository International
(London, United Kingdom)

Book Description Yale University Press, United States, 2016. Paperback. Condition: New. Reprint. Language: English. Brand new Book. A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate. His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement. In this book, Prusiner tells the remarkable story of his discovery of prions-infectious proteins that replicate and cause disease but surprisingly contain no genetic material-and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner's hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer's, Parkinson's, Lou Gehrig's and other devastating diseases of the brain?. Seller Inventory # BZV9780300216905

More information about this seller | Contact this seller

Buy New
US$ 21.31
Convert currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, rates & speeds
Stock Image

5.

Prusiner, Stanley B.
Published by Yale University Press (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 1
Seller:
Ergodebooks
(Richmond, TX, U.S.A.)

Book Description Yale University Press, 2016. Paperback. Condition: New. Seller Inventory # DADAX0300216904

More information about this seller | Contact this seller

Buy New
US$ 17.71
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds
Stock Image

6.

Stanley B. Prusiner
Published by Yale University Press, United States (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 10
Seller:
Book Depository hard to find
(London, United Kingdom)

Book Description Yale University Press, United States, 2016. Paperback. Condition: New. Reprint. Language: English. Brand new Book. A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate. His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement. In this book, Prusiner tells the remarkable story of his discovery of prions-infectious proteins that replicate and cause disease but surprisingly contain no genetic material-and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner's hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer's, Parkinson's, Lou Gehrig's and other devastating diseases of the brain?. Seller Inventory # BZV9780300216905

More information about this seller | Contact this seller

Buy New
US$ 22.99
Convert currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, rates & speeds
Stock Image

7.

Stanley B. Prusiner
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 11
Seller:
Grand Eagle Retail
(Wilmington, DE, U.S.A.)

Book Description 2016. Paperback. Condition: New. Paperback. A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases In 1997, Stanley B. Prusiner received a Nobel Prize, the world.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 344 pages. 0.450. Seller Inventory # 9780300216905

More information about this seller | Contact this seller

Buy New
US$ 29.66
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds
Stock Image

8.

Prusiner, Stanley B.
Published by Yale University Press (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Softcover Quantity Available: 1
Seller:
Irish Booksellers
(Portland, ME, U.S.A.)

Book Description Yale University Press, 2016. Condition: New. book. Seller Inventory # M0300216904

More information about this seller | Contact this seller

Buy New
US$ 17.41
Convert currency

Add to Basket

Shipping: US$ 19.77
Within U.S.A.
Destination, rates & speeds
Stock Image

9.

Stanley B. Prusiner
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 11
Seller:
AussieBookSeller
(Lidcombe, NSW, Australia)

Book Description 2016. Paperback. Condition: New. Paperback. A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases In 1997, Stanley B. Prusiner received a Nobel Pri.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 344 pages. 0.450. Seller Inventory # 9780300216905

More information about this seller | Contact this seller

Buy New
US$ 27.92
Convert currency

Add to Basket

Shipping: US$ 37.00
From Australia to U.S.A.
Destination, rates & speeds
Stock Image

10.

Prusiner, Stanley B.
Published by Yale Univ Pr (2016)
ISBN 10: 0300216904 ISBN 13: 9780300216905
New Paperback Quantity Available: 1
Seller:
Revaluation Books
(Exeter, United Kingdom)

Book Description Yale Univ Pr, 2016. Paperback. Condition: Brand New. 1st edition. 320 pages. 9.25x6.00x1.25 inches. In Stock. Seller Inventory # zk0300216904

More information about this seller | Contact this seller

Buy New
US$ 30.43
Convert currency

Add to Basket

Shipping: US$ 44.60
From United Kingdom to U.S.A.
Destination, rates & speeds