Polymers in Medicine: Biomedical and Pharmacological Applications (NATO Advanced Study Institute Series)

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9780306413605: Polymers in Medicine: Biomedical and Pharmacological Applications (NATO Advanced Study Institute Series)

This book contains the collected papers presented at the Inter­ national Symposium on Polymers in Medicine, Biomedical and Pharma­ cological Applications, which was held at Porto Cervo, Italy, May 24-28, 1982. To the best of our knowledge, this symposium was the first to be organized in Italy entirely devoted to the several aspects of the use of synthetic and semisynthetic macromolecular materials in the field of biomedical and pharmacological applications. The inten~ tion of the Organizing Committee of the symposium was the promotion of a scientific and cultural initiative to gain the attention of various experts in line research of the potential of suitably de­ signed "man-made" polymeric materials in biomedical applications. With highly qualified and worldwide attendance, the above goal was fully satisfied. Indeed the opportunity of meeting to­ gether in a well conceived and discreet corner of the world, scien­ tists with different cultural backgrounds and objectives helped ex­ tend the meaning of the symposium far beyond the Italian borders and the perspectives of the National Research Council of Italy (CNR) , the major sponsor of the meeting.

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Product Description:

The utilization of polymers in medicine has become a reality in the last decade. This book is a concise presentation of the fundamentals, applications, and methods of optimization of polymeric drugs and polymeric drug delivery systems for medicinal purposes. The basic rationale for the use of polymeric drugs and polymer delivery systems is the possibility to alter the pharmacokinetics and pharmacodynamics of therapeutic agents so as to maintain an adequate therapeutic environment at the site of disfunction for an extended period of time.
The primary objectives for using polymeric drugs and polymeric drug delivery systems are to introduce new and efficient methods of drug administration, to improve efficacy and patient compliance, to decrease toxicity, and to ensure safety. The following factors influence the design and performance of polymers for medicinal applications: disease, drug properties, type of therapy (acute or chronic), physiology of the patient, administration route, and the site requiring therapy.

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Chiellini, Emo, Giusti, Paolo
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Italy) International Symposium on Polymers in Medicine: Biomedical and Pharmacological Applications (1982 : Porto Cervo; Paolo Giusti; Emo Chiellini
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