Phospholipases are a class of ubiquitous enzymes that have in common their substrate and the fact that they are all esterases. Beyond that, they are a diverse group of enzymes that fall into two broad categories, the acyl hydro lases and the phosphodiesterases. The former group is made up of the phos pholipases Al and A, phospholipase B, and the lysophospholipases. On the 2 other hand, the phosphodiesterases are the phospholipases C and D. The scheme indicates the site of attack of each type of phospholipase. PLA 1 PLB j ft 0\ -C-O-C-R d 2 I 1 R-C-0-C-H 0 2 /H2-6-0-U-0-x PLA, 6- '" PLC PLD The lysophospholipases, not shown, have in some cases properties similar to phospholipase B and are known to attack the acyl ester at either position 1 or position 2 of the glycerol backbone. Furthermore, some of the phos pholipases C and D do not hydrolyze phosphoglycerides but use sphingo myelinase as their substrate. These phospholipases C are also referred to as sphingomyelinases. The products of that reaction are phosphocholine plus ceramide.
"synopsis" may belong to another edition of this title.
Book Description Springer, 1987. Hardcover. Book Condition: New. 1. This item is printed on demand. Bookseller Inventory # DADAX0306426218