The Genetic Basis of Alcohol and Drug Actions

0 avg rating
( 0 ratings by Goodreads )
 
9780306438684: The Genetic Basis of Alcohol and Drug Actions
View all copies of this ISBN edition:
 
 

HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide­ ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod­ gers, 1966; McClearn, 1968).

"synopsis" may belong to another edition of this title.

Buy New View Book
List Price: US$ 229.99
US$ 203.75

Convert Currency

Shipping: US$ 3.99
Within U.S.A.

Destination, Rates & Speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

1.

Crabbe Jr., J. C.
Published by Springer Science+Business Media (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Quantity Available: > 20
Print on Demand
Seller:
Pbshop
(Wood Dale, IL, U.S.A.)
Rating
[?]

Book Description Springer Science+Business Media, 1991. HRD. Condition: New. New Book.Shipped from US within 10 to 14 business days.THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IP-9780306438684

More information about this seller | Contact this seller

Buy New
US$ 203.75
Convert Currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, Rates & Speeds

2.

Published by Springer Science+Business Media, United States (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 1
Seller:
Book Depository International
(London, United Kingdom)
Rating
[?]

Book Description Springer Science+Business Media, United States, 1991. Hardback. Condition: New. 1991 ed.. Language: English . Brand New Book. HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide- ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod- gers, 1966; McClearn, 1968). Seller Inventory # AAS9780306438684

More information about this seller | Contact this seller

Buy New
US$ 221.57
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

3.

Crabbe Jr., J. C.
Published by Springer Science+Business Media (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Quantity Available: > 20
Print on Demand
Seller:
Books2Anywhere
(Fairford, GLOS, United Kingdom)
Rating
[?]

Book Description Springer Science+Business Media, 1991. HRD. Condition: New. New Book. Delivered from our US warehouse in 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND.Established seller since 2000. Seller Inventory # IP-9780306438684

More information about this seller | Contact this seller

Buy New
US$ 213.32
Convert Currency

Add to Basket

Shipping: US$ 12.60
From United Kingdom to U.S.A.
Destination, Rates & Speeds

4.

Published by Springer Science+Business Media, United States (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 1
Seller:
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Springer Science+Business Media, United States, 1991. Hardback. Condition: New. 1991 ed.. Language: English . Brand New Book. HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide- ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod- gers, 1966; McClearn, 1968). Seller Inventory # AAS9780306438684

More information about this seller | Contact this seller

Buy New
US$ 227.63
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

5.

Published by Springer Science+Business Media, United States (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 10
Seller:
Book Depository hard to find
(London, United Kingdom)
Rating
[?]

Book Description Springer Science+Business Media, United States, 1991. Hardback. Condition: New. 1991 ed.. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide- ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod- gers, 1966; McClearn, 1968). Seller Inventory # LIE9780306438684

More information about this seller | Contact this seller

Buy New
US$ 238.27
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

6.

J.C. CRABBE JR.
Published by Springer (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 1
Seller:
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Springer, 1991. Hardback. Condition: NEW. 9780306438684 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. For all enquiries, please contact Herb Tandree Philosophy Books directly - customer service is our primary goal. Seller Inventory # HTANDREE0269407

More information about this seller | Contact this seller

Buy New
US$ 237.93
Convert Currency

Add to Basket

Shipping: US$ 11.17
From United Kingdom to U.S.A.
Destination, Rates & Speeds

7.

J.C. Crabbe Jr. (editor), R.A. Harris (editor)
Published by Springer US 1991-10-31, Berlin (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 10
Seller:
Blackwell's
(Oxford, OX, United Kingdom)
Rating
[?]

Book Description Springer US 1991-10-31, Berlin, 1991. hardback. Condition: New. Seller Inventory # 9780306438684

More information about this seller | Contact this seller

Buy New
US$ 248.01
Convert Currency

Add to Basket

Shipping: US$ 8.40
From United Kingdom to U.S.A.
Destination, Rates & Speeds

8.

John C. Crabbe, R. Adron Harris
Published by Springer Science+Business Media
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 1
Seller:
THE SAINT BOOKSTORE
(Southport, United Kingdom)
Rating
[?]

Book Description Springer Science+Business Media. Hardback. Condition: new. BRAND NEW, The Genetic Basis of Alcohol and Drug Actions, John C. Crabbe, R. Adron Harris, HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide- ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod- gers, 1966; McClearn, 1968). Seller Inventory # B9780306438684

More information about this seller | Contact this seller

Buy New
US$ 260.91
Convert Currency

Add to Basket

Shipping: US$ 9.70
From United Kingdom to U.S.A.
Destination, Rates & Speeds

9.

Crabbe, John
Published by Springer (2016)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Paperback Quantity Available: 1
Print on Demand
Seller:
Ria Christie Collections
(Uxbridge, United Kingdom)
Rating
[?]

Book Description Springer, 2016. Paperback. Condition: New. PRINT ON DEMAND Book; New; Publication Year 2016; Not Signed; Fast Shipping from the UK. No. book. Seller Inventory # ria9780306438684_lsuk

More information about this seller | Contact this seller

Buy New
US$ 265.22
Convert Currency

Add to Basket

Shipping: US$ 5.40
From United Kingdom to U.S.A.
Destination, Rates & Speeds

10.

Crabbe, John C., Jr./ Harris, R. Adron (Editor)
Published by Plenum Pub Corp (1991)
ISBN 10: 0306438682 ISBN 13: 9780306438684
New Hardcover Quantity Available: 1
Seller:
Revaluation Books
(Exeter, United Kingdom)
Rating
[?]

Book Description Plenum Pub Corp, 1991. Hardcover. Condition: Brand New. 1st edition. 404 pages. 9.50x6.50x1.00 inches. In Stock. Seller Inventory # z-0306438682

More information about this seller | Contact this seller

Buy New
US$ 269.95
Convert Currency

Add to Basket

Shipping: US$ 8.39
From United Kingdom to U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book