Phthalates and Cumulative Risk Assessment: The Tasks Ahead - Softcover

National Research Council; Division On Earth And Life Studies; Board On Environmental Studies And Toxicology; Committee On The Health Risks Of Phthalates

Softcover

ISBN 10: 0309128412 ISBN 13: 9780309128414

Publisher: National Academies Press, 2009

Synopsis

People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals.
Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Table of Contents

• Front Matter
• Summary
• 1 Introduction
• 2 Phthalate Exposure Assessment in Humans
• 3 Toxicity Assessment
• 4 Current Practice in Risk Assessment and Cumulative Risk Assessment
• 5 Cumulative Risk Assessment of Phthalates and Related Chemicals
• 6 Data Gaps and Research Needs
• Appendix A: Statement of Task
• Appendix B: Biographic Information on the Committee on Health Risks of Phthalates
• Appendix C: Analysis of a Mixture of Five Phthalates: A Case Study
• Appendix D: Evaluating Multiple End Points Simultaneously in a Mixture of Three Antiandrogens: A Case Study

About this edition

• Publisher: National Academies Press
• Publication date: 2009
• ISBN 10: 0309128412
• ISBN 13: 9780309128414
• Binding: Paperback
• Number of pages: 208