Medical statistics is increasingly important in many areas of medicine and the growing rise of evidence-based medicine will make it still more so. It has critical applications in clinical trials, genetic research, epidemiology and in the design and analysis of medical experiments and surveys. Statistical analyses are now widely reported in published papers and no researcher or practitioner in the health sciences can afford to ignore this crucial subject. The Encyclopaedic Companion to Medical Statistics is a straightforward and comprehensive reference source that will be an invaluable guide for those with no formal statistical background and a handy reference for those who do know some statistics. With coverage ranging from simple definitions and basic tests to the latest techniques used at the cutting edge of medical research, this book will be invaluable to anyone working in this field.
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Brian S. Everitt - Professor Emeritus, King's College London. After 35 Years at the Institute of Psychiatry, University of London, Brian Everitt retired in May 2004. Author of approximately 100 journal articles and over 50 books on statistics, and also -co-editor of Statistical Methods in Medical Research. Writing continues apace in retirement but now punctuated by tennis, walks in the country, guitar playing and visits to the gym, rather than by committees, committees and more committees.
Christopher R. Palmer, founding Director of Cambridge University's Centre for Applied Medical Statistics, regularly teaches and collaborates with current and future doctors. His first degree was from Oxford, while graduate and post-doctoral studies were in the USA (at UNC-Chapel Hill and Harvard). He has shifted from mathematical towards applied statistics, with particular interest in the ethics of clinical trials and the use of flexible designs whenever appropriate. Fundamentally, he likes to promote sound statistical thinking in all areas of medical research and hopes this volume might help towards that end. Chris served as Deputy or Acting Editor of Statistics in Medicine, 1996-2000, and is a long-standing statistical reviewer for The Lancet. he and his wife have three children they consider to be more than Statistically significant.
During the last twenty years statistical methodology has become of central importance in research studies in medicine and also in day-to-day clinical practice. The medical literature is now liberally punctuated not only with relatively routine statistical terms such as p-value, t-test, confidence interval, and correlation, but also with more esoteric items such as hazard function, multilevel model, generalized estimating equations and crossover design. Consequently researchers in medicine and clinicians who are not primarily statisticians need to have a source that provides readable accounts of these terms so that they can understand at least the essence of the statistical aspects of both the design and analysis of a reported investigation. The Encyclopedic Companion to Medical Statistics is that source, containing readable accounts of over 500 statistical topics central to current medical research, with each entry being written by an expert in the field. Examples and graphical material supplement the written material in many entries, and extensive cross-referencing sign posts the reader to other entries that are likely to be relevant.
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