The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria and Explanatory Notes

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9780387876658: The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria and Explanatory Notes
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This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.

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Thyroid fine needle aspiration is one of the most commonly performed cytologic procedures and is the standard diagnostic method for managing the patient with a thyroid nodule.  Until now, there has been no uniform system for reporting the results of thyroid fine needle aspiration (FNA) in the U.S.

The terminology described in this book is an important advance in the field of cytopathology. It represents the results of the multidisciplinary National Cancer Institute Thyroid Fine Needle Aspiration State of The Science Conference, held in Bethesda, MD in October, 2007.

The Bethesda System for Reporting Thyroid Cytopathology will provide the reader with a unified approach to diagnosing and reporting thyroid FNA interpretations. It will serve as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists.

About the Author:

Syed Z. Ali, MD
Professor of Pathology
The Johns Hopkins Hospital
Baltimore, MD
USA

Edmund S. Cibas, MD
Professor of Pathology
Harvard Medical School
Brigham and Women's Hospital
Boston, MA
USA

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