Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions - Softcover

Softcover

ISBN 10: 0443316988 ISBN 13: 9780443316982

Publisher: Academic Press, 2025

Synopsis

Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.

In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

• Considers the therapeutic application of phytochemicals for the treatment of metabolic diseases, including cardiovascular disease, obesity, and type 2 diabetes
• Explores phytochemicals at the molecular level, covering signaling pathways of oxidative stress, mitophagy, inflammasomes, molecular chaperones, receptors, and how these mechanisms can be used to treat diseases
• Discusses the use of artificial intelligence and high-throughput omics technologies in plant-based drug discovery

About this title

About the Authors

Dr. Mamta Bisht is presently working as an Assistant Professor in the Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University (NAAC A+), Dehradun, Uttarakhand, India. She has been actively involved in the extraction, isolation, and characterization of “natural products” obtained from the medicinal and aromatic plants with bioactivity for the last 8 years. Besides this, her analytical skills are in GC, GC-MS, HPLC, Prep-HPLC, and HPTLC. Furthermore, she is equally involved in the promotion of endangered and economically important species from the youngest Himalayan region. She has published more than 20 papers in peer-reviewed international journals and seven book chapters. Further, she has participated in more than 10 conferences, including national and international ones. She is a lifetime member of the Indian Science Congress Association. Under her guidance, many PG and UG students successfully completed their project thesis, and some PhD students are currently working with her

Prof (Dr.) Ajay Singh is currently working as Director SALS and Dean Research & Studies in Uttaranchal University, Dehradun, India. He has more than 20 years (including R&D industrial research) of research experience. He has published more than 70 research articles in reputed journals and several chapters during his research work. More than 5 patents and projects are also credited in his account. He has also written 2 academic books for UG and PG students. He has guided more than 50 students for Project thesis of U.G and P. G. students and awarded more than 5 Ph. D students and several are registered under him. He is the receipt of young Scientist award by Scientific Planet Society India and several other awards.

Dr. Akhileshwar Kumar Srivastava works as a Research Associate (ICMR) at CSIR-Central Food Technological Research Institute, Mysore, India. In his 11 years of research, he has published more than 18 research articles in reputed international journals, along with 4 books and 11 book chapters. His research specialization is primarily in the area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology associated with targeting virulent factors of diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, USA, on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel. He is also a life member fellow in the Indian Science Congress and the Agriculture, Nutrition and Health Academy, UK.

From the Back Cover

Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an overview of the molecular mechanisms of phytochemicals and how they can be utilized in the treatment of metabolic diseases. The book opens with an introduction to metabolic diseases and the significance of phytochemicals in tackling these disorders, before considering their molecular mechanisms and how they can impact health and disease. Chapters will cover topics including oxidative stress, epigenetic mechanisms, mitophagy, and targeting molecular chaperones. Molecular targets of plant nutraceuticals and phytochemical for specific treatment of obesity, cardiovascular disease and type 2 diabetes will also be covered. The book also considers technological advances such as AI and nanotechnology and their impact in this area, as well as opportunities and challenges for improving the use of plant molecules in the treatment of metabolic disorders. This is a useful book for researchers working across the fields of molecular biology, biochemistry, pharmacology, phytochemistry, drug discovery, biotechnology and related areas.

Edition details

• Publisher: Academic Press
• Publication date: 2025
• Language: English
• ISBN 10: 0443316988
• ISBN 13: 9780443316982
• Binding: Paperback
• Edition number: 1
• Number of pages: 648
• Editor: Bisht PhD Mamta, Singh PhD Ajay, Srivastava PhD Akhileshwar Kumar