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Synopsis
Rigorous statistical analysis methods for human genetics application
Statistics in Human Genetics explores the statistical analysis methods that are critical to good science. Beginning with a brief review of genes, gene structure, variation, and terminology, the book moves into analysis of segregation, genetic linkage, allelic associations, and continuity for a wide range of conditions. From the classic Hardy-Weinberg equation to advanced modeling, algorithms and more, this book provides authoritative guidance toward methods, analysis, and applications for anyone performing quantitative analysis of human genetics.
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From the Back Cover
In human genetic research sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail.
About the Author
Pak Chung Sham is a psychiatric geneticist. He holds the Suen Chi-Sun Professorship in Clinical Science at the University of Hong Kong, where he is also the Chair Professor in Psychiatric Genomics, Director of the Centre for Genomic Sciences, and Director of Academic Developments in the Department of Psychiatry.
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- PublisherWiley
- Publication date1997
- ISBN 10 0470689285
- ISBN 13 9780470689288
- BindingPaperback
- LanguageEnglish
- Edition number1
- Number of pages300
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Statistics in Human Genetics
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John Wiley & Sons and Hodder Headline Group, New York and London, 1998
ISBN 10: 0470689285
ISBN 13: 9780470689288
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Statistics in Human Genetics (Paperback)
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Paperback. Condition: new. Paperback. Rigorous statistical analysis methods for human genetics application Statistics in Human Genetics explores the statistical analysis methods that are critical to good science. Beginning with a brief review of genes, gene structure, variation, and terminology, the book moves into analysis of segregation, genetic linkage, allelic associations, and continuity for a wide range of conditions. From the classic Hardy-Weinberg equation to advanced modeling, algorithms and more, this book provides authoritative guidance toward methods, analysis, and applications for anyone performing quantitative analysis of human genetics. Rigorous statistical analysis methods for human genetics application Statistics in Human Genetics explores the statistical analysis methods that are critical to good science. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9780470689288
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