Protein NMR Spectroscopy: Principal Techniques and Applications

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9780470721933: Protein NMR Spectroscopy: Principal Techniques and Applications

Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. The dramatic advances in NMR techniques have led to corresponding advances in the ability of NMR to study structure, dynamics and interactions of biological macromolecules in solution under close to physiological conditions. This volume focuses on the use of NMR to study proteins.

NMR can be used to determine detailed three-dimensional structures of proteins in solution. Furthermore, it provides information about conformational or chemical exchange, internal mobility and dynamics at timescales varying from pcoseconds to seconds. It is the primary technique used to obtain information on intrinsically disordered (unfolded) proteins, since these proteins will not crystallize easily. NMR is also a very powerful method for the study of interactions of protein with other molecules, whether small molecules (including drugs), nuclear acids or other proteins.

This up-to-date volume covers NMR techiniques and their application to proteins, with a focus on practical details. This book will provide a newcomer to NMR with the practical guidance in order to carry out successful experiments with proteins and to analyze the resulting spectra. Those who are familiar with the chemical applications of NMR will also find is useful in understanding the special requirements of protien NMR.

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Nuclear Magnetic Resonance (NMR) spectroscopy, a physicalphenomenon based upon the magnetic properties of certain atomicnuclei, has found a wide range of applications in life sciencesover recent decades. This up-to-date volume covers NMR techniquesand their application to proteins, with a focus on practicaldetails. Providing newcomers to NMR with practical guidance tocarry out successful experiments with proteins and analyze theresulting spectra, those familiar with the chemical applications ofNMR will also find it useful in understanding the specialrequirements of protein NMR.

Review:

“This is a must for anyone interested in using solution NMR to study proteins.  Summing Up: Highly recommended.  Graduate students, researchers/faculty, and professionals/practitioners.”  (Choice, 1 April 2012)

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Book Description John Wiley and Sons Ltd, United States, 2011. Hardback. Book Condition: New. 1. Auflage. 250 x 174 mm. Language: English . Brand New Book. Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. This up-to-date volume covers NMR techniques and their application to proteins, with a focus on practical details. Providing newcomers to NMR with practical guidance to carry out successful experiments with proteins and analyze the resulting spectra, those familiar with the chemical applications of NMR will also find it useful in understanding the special requirements of protein NMR. Bookseller Inventory # AAH9780470721933

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Book Description John Wiley and Sons Ltd, United States, 2011. Hardback. Book Condition: New. 1. Auflage. 250 x 174 mm. Language: English . Brand New Book. Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. This up-to-date volume covers NMR techniques and their application to proteins, with a focus on practical details. Providing newcomers to NMR with practical guidance to carry out successful experiments with proteins and analyze the resulting spectra, those familiar with the chemical applications of NMR will also find it useful in understanding the special requirements of protein NMR. Bookseller Inventory # AAH9780470721933

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