Gas Chromatography: Biochemical, Biomedical, and Clinical Applications (Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications)

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9780471010487: Gas Chromatography: Biochemical, Biomedical, and Clinical Applications (Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications)
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Concerned with the use of gas chromatography to solve biological and biochemical problems. Provides thorough coverage of the methods involved--basic principles and equipment, multidimensional techniques, detectors and derivatization techniques. Several chapters deal specifically with biological applications such as the biological profiling and monitoring of drug therapy, and the detection of urinary acids and steroids, prostaglandins, fatty acids and lipids. Treats drug abuse detection, toxicological problems and the determination of heavy metals in blood plasma. The use of gas chromatography for identifying bacteria in the clinical microbiology laboratory is also discussed.

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From the Inside Flap:

Gas chromatography is the subtlest—and possibly the most expert—chemical detective in the complex world of materials analysis. When combined with many of the sensitive detectors now available, gas chromatography provides a means of investigating ultra-trace levels of compounds—even in a complex mixture. It is not surprising that gas chromatography is viewed as the ideal technique for investigating the complex chemical systems often encountered in biochemical, biomedical, and clinical studies. This is the first handbook of modern gas chromatography techniques that addresses those essential to the complex separations demanded in biochemical, biomedical, and clinical studies, subjects often overlooked in other textbooks. Essential to the scientist who needs only the representative GC techniques useful in real applications, Gas Chromatography provides the muscular basics of the discipline—without needlessly detailed theory. Its balanced and timely look at both techniques and applications is designed to meet the needs of both novices and experienced users of GC. Inside you’ll find discussion of:

  • Characteristics of modern gas chromatography instrumentation
  • Multidimensional gas chromatography techniques and applications
  • Qualitative and quantitative methods of analysis for gas chromatography
  • Derivatization techniques
  • Gas chromatography profiling in biomedical investigations
  • Fatty acids, fatty acids containing lipids, and their gas chromatographic analysis
  • Gas chromatography of micro-organisms
  • Gas chromatography of organometallic compounds
  • Applications of gas chromatography in clinical and forensic toxicology
  • The progress of analytical chemistry in sport drug testing
Clean and concise in its approach to technical specifics, the text will enable the reader to get up-to-speed quickly in the important topics of GC. Its expansive treatment of the biochemical, biomedical, and clinical uses of gas chromatography—simply unavailable in other texts—makes Gas Chromatography unique. Clinical and forensic chemists, research chemists, laboratory analysts and technicians, lab managers, physicians, medical researchers, and students of medicine will find all the technical expertise essential to the enhancement of their day-to-day research assembled in this one valuable reference.

About the Author:

About the editor Ray E. Clement, PhD, is Senior Scientist with the Ontario Ministry of the Environment, Laboratory Services Branch. He is also Adjunct Executive Director of the Canadian Institute for Research in Atmospheric Chemistry and Honorary Professor at the University of Western Ontario, Chemistry Department. He has served on the editorial board of the journal Chemosphere and published 75 articles in numerous scientific publications. His books include Basic Gas Chromatography--Mass Spectrometry: Principles and Techniques and Emissions from Combustion Processes: Origin, Analysis, Fate. Dr. Clement received his PhD in analytical chemistry from the University of Waterloo.

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Published by Wiley-Interscience (1990)
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