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Provides comprehensive information on the most useful protective groups for the hydroxyl, amino, carboxyl, carbonyl, and sulfhydryl groups. Discusses the chemistry of the classes of protective groups, as well as that of the individual protective groups within the class using structures, equations and references. Reactivity Charts for each class of protective group serve as an aid in their appropriate choice and provide estimates of their relative reactivities toward 108 prototype reagents.
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The Most Comprehensive Guide to Protective Groups in Organic Synthesis Currently Available
For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence.
The Fourth Edition includes significant developments in protective group chemistry since 1998. In addition to incorporating new protective groups now available to the synthetic organic chemist, such as the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines, the book also covers new techniques for the formation and cleavage of existing protective groups, providing the most relevant and useful examples to illustrate each methodology. The content is organized around the functional group to be protected (ethers, acids, carbonyl groups, amines, amides, phenols, etc.), and ranges from the simplest to the most complex highly specialized protective groups.
New features of the Fourth Edition include:
PETER G. M. WUTS, PHD, is a Senior Research Fellow at Pfizer in Ann Arbor, Michigan.
The late THEODORA W. GREENE, PHD, was the librarian for the Rowland Institute for Science and former assistant editor for Organic Syntheses.
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Book Description Wiley, 1981. Hardcover. Condition: New. Never used!. Seller Inventory # P110471057649
Book Description Wiley. Hardcover. Condition: New. 0471057649 New Condition. Seller Inventory # NEW99.1174449
Book Description Wiley, 1981. Condition: New. book. Seller Inventory # M0471057649