Handbook of Nucleoside Synthesis - Softcover

Vorbrüggen, Helmut; Ruh-Pohlenz, Carmen

Softcover

ISBN 10: 0471093831 ISBN 13: 9780471093831

Publisher: Wiley-Interscience, 2001

Synopsis

Handbook of Nucleoside Synthesis includes descriptive information regarding the three principal types of nucleoside forming reactions: the Fusion Reaction, the Metal Salt Procedure, and the Hilbert-Johnson Reaction, as well as other miscellaneous methods.

About this title

About the Author

HELMUT VORBRUGGEN is Professor of Chemistry at the Free University in Berlin, Germany.
CARMEN RUH-POHLENZ is Research Scientist at Schering AG in Berlin, Germany.

From the Back Cover

A comprehensive survey of established and experimental methods in nucleoside synthesis

This volume presents a comprehensive review of nucleoside synthesis with a uniquely broad perspective. It describes the three principal types of nucleoside-forming reactions the fusion reaction, the metal salt procedure, and the Hilbert-Johnson reaction as well as a number of other methods, and presents a broad overview of alternative chemical methods for synthesis.

This comprehensive discussion includes a survey of experimental protocols for nucleoside synthesis, instructions on preparing components for the reaction, and a sampling of precise experimental procedures for the Vorbrüggen glycosylation reaction. Protocols for a variety of Lewis acid catalysts and carbohydrate precursors are also provided.

An exhaustive tabular survey of glycosylation reactions with nucleobases covers approximately twenty years of literature. These tables are designed for quick visual inspection and form a primary literature resource for researchers in the discipline.

Handbook of Nucleoside Synthesis is an essential resource for those working in nucleosides and oligonucleotides. This thoughtful and well-organized volume includes over 1,400 references that serve the knowledgeable researcher s every need. Those just entering the field will find it to be an indispensable survey of the experimental aspects of nucleoside synthesis.

This volume presents a comprehensive review of nucleoside synthesis with a uniquely broad perspective. It describes the three principal types of nucleoside-forming reactions–the fusion reaction, the metal salt procedure, and the Hilbert-Johnson reaction–as well as a number of other methods, and presents a broad overview of alternative chemical methods for synthesis.

This comprehensive discussion includes a survey of experimental protocols for nucleoside synthesis, instructions on preparing components for the reaction, and a sampling of precise experimental procedures for the Vorbrüggen glycosylation reaction. Protocols for a variety of Lewis acid catalysts and carbohydrate precursors are also provided.

An exhaustive tabular survey of glycosylation reactions with nucleobases covers approximately twenty years of literature. These tables are designed for quick visual inspection and form a primary literature resource for researchers in the discipline.

Handbook of Nucleoside Synthesis is an essential resource for those working in nucleosides and oligonucleotides. This thoughtful and well-organized volume includes over 1,400 references that serve the knowledgeable researcher’s every need. Those just entering the field will find it to be an indispensable survey of the experimental aspects of nucleoside synthesis.

Edition details

• Publisher: Wiley-Interscience
• Publication date: 2001
• Language: English
• ISBN 10: 0471093831
• ISBN 13: 9780471093831
• Binding: Paperback
• Edition number: 1
• Number of pages: 646