Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology

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9780471246435: Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology

This book is Part A in a subseries entitled "Amino Acid Metabolism". Topics in Part A should be of immediate interest to those who are broadly concerned with amino acid assimilation and metabolism. Investigators interested in enzyme mechanism and regulation will also find this volume especially valuable.

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From the Back Cover:

Volume 75 in the classic series Advances in Enzymology and Related Areas of Molecular Biology explores the area of protein evolution. This volume considers mechanisms of protein evolution broadly, including the use of evolutionary archeology to trace protein evolution, the conservation of structure–rather than sequence–in protein evolution, and the use of directed evolution to create new enzyme activities.

Chapters include:

  • Molecular Paleoscience: Systems Biology from the Past
  • A Structure-Centric View of Protein Evolution, Design, and Adaptation
  • Mechanisms of Protein Evolution and Their Applications to Protein Engineering
  • Novel Enzymes Through Design and Evolution

About the Author:

ERIC J. TOONE is Professor of Chemistry and Professor of Biochemistry at Duke University in Durham, North Carolina.

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