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This practical, comprehensive resource provides the strategic tools necessary for designing an up-to-date safety assessment program, and gives you the practical tools you need to implement it. The book includes a comprehensive discussion of regulatory requirements, project management essentials, screens and phasing, along with highly specific advice on testing and assessment from acknowledged experts in toxicology. Every major test methodology is covered: Acute, chronic, and subchronic toxicity studies. Developmental and reproductive toxicity testing. Pulmonary assessment. Irritation and local tissue tolerance testing. Current topics are included, from immunotoxicology, to nonrodent experiment design, to the future of In Vitro techniques. Avoiding dry mathematical and theoretical discussion in favor of practical guidance, this is the best reference available for understanding and performing safety assessments.
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About the authors RUEDIGER VOSSEN is an Advisory Systems Engineer with the IBM Corporation, where he has worked since 1967. He has also held positions in computer operations, systems and applications programming, systems engineering, and teaching. THOMAS E. CURTIN has held a variety of positions with the IBM Corporation since 1968, chiefly in I/S. He spent ten years in the Information Systems organization of the company's General Technology Division, working on projects supporting advanced manufacturing processes. Mr. Curtin has developed and taught courses on software application development at the IBM Information Systems Management Institute in New York City and currently teaches senior executive programs at the IBM Advanced Business Institute. He holds an MBA from the University of Connecticut.From the Back Cover:
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