The Stille Reaction

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9780471312734: The Stille Reaction

A guide to making optimal use of one of the most important tools available to today's synthetic organic chemist

Compatible with virtually all functional groups without protection and capable of forming carbon-carbon bonds under neutral conditions-often with complete stereospecificity-the Stille reaction is an indispensable component of the synthetic organic chemist's toolkit. In the years since Stille's pioneering work, chemists have developed a vast number of applications for this incredibly versatile metal-catalyzed cross-coupling reaction. This paperback edition of the 50th volume in the definitive Organic Reactions series describes many of those uses.

Drawing upon their considerable experience as professional synthetic organic chemists who have worked extensively with the Stille reaction, the authors approach their subject from the preparative viewpoint, paying particular attention throughout to limitations, interfering influences, effects of structure, and the selection of experimental techniques. Focusing primarily on the single reaction of the Stille reaction, they provide comprehensive coverage of:
* Experimental conditions and selecting optimal experimental parameters
* Traditional and recently developed experimental procedures
* Side reactions and techniques for avoiding them
* Documented reactions-33 tables list 570 reactions, complete withconditions, yields, structures of major products, and common failures
* Easy-to-follow recipes for casual users of the Stille reaction

The Stille Reaction is an indispensable working resource for all synthetic organic chemists, especially medicinal chemists. It is also an excellent graduate-level text for students of organic and medicinal chemistry.

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About the Author:

VITTORIO FARINA, PhD, is Director at the Boehringer Ingelheim Pharmaceuticals Department of Chemical Development.

VENKAT KRISHNAMURTHY, PhD, is a research chemist with Occidental Chemical Corporation.

WILLIAM J. SCOTT is a research chemist with the Bayer Corporation Institute of Chemistry, Department of Medicinal Chemistry.

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Farina, Vittorio; Krishnamurthy, Venkat; Scott, William J.
Published by John Wiley and Sons Ltd, United States (1998)
ISBN 10: 0471312738 ISBN 13: 9780471312734
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Book Description John Wiley and Sons Ltd, United States, 1998. Paperback. Book Condition: New. New.. 231 x 154 mm. Language: English . Brand New Book ***** Print on Demand *****.A guide to making optimal use of one of the most important tools available to today s synthetic organic chemist Compatible with virtually all functional groups without protection and capable of forming carbon-carbon bonds under neutral conditions-often with complete stereospecificity-the Stille reaction is an indispensable component of the synthetic organic chemist s toolkit. In the years since Stille s pioneering work, chemists have developed a vast number of applications for this incredibly versatile metal-catalyzed cross-coupling reaction. This paperback edition of the 50th volume in the definitive Organic Reactions series describes many of those uses. Drawing upon their considerable experience as professional synthetic organic chemists who have worked extensively with the Stille reaction, the authors approach their subject from the preparative viewpoint, paying particular attention throughout to limitations, interfering influences, effects of structure, and the selection of experimental techniques. Focusing primarily on the single reaction of the Stille reaction, they provide comprehensive coverage of: Experimental conditions and selecting optimal experimental parameters Traditional and recently developed experimental procedures Side reactions and techniques for avoiding them Documented reactions-33 tables list 570 reactions, complete withconditions, yields, structures of major products, and common failures Easy-to-follow recipes for casual users of the Stille reaction The Stille Reaction is an indispensable working resource for all synthetic organic chemists, especially medicinal chemists. It is also an excellent graduate-level text for students of organic and medicinal chemistry. Bookseller Inventory # AAV9780471312734

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Farina, Vittorio; Krishnamurthy, Venkat; Scott, William J.
Published by John Wiley and Sons Ltd, United States (1998)
ISBN 10: 0471312738 ISBN 13: 9780471312734
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Book Description John Wiley and Sons Ltd, United States, 1998. Paperback. Book Condition: New. New.. 231 x 154 mm. Language: English . Brand New Book ***** Print on Demand *****. A guide to making optimal use of one of the most important tools available to today s synthetic organic chemist Compatible with virtually all functional groups without protection and capable of forming carbon-carbon bonds under neutral conditions-often with complete stereospecificity-the Stille reaction is an indispensable component of the synthetic organic chemist s toolkit. In the years since Stille s pioneering work, chemists have developed a vast number of applications for this incredibly versatile metal-catalyzed cross-coupling reaction. This paperback edition of the 50th volume in the definitive Organic Reactions series describes many of those uses. Drawing upon their considerable experience as professional synthetic organic chemists who have worked extensively with the Stille reaction, the authors approach their subject from the preparative viewpoint, paying particular attention throughout to limitations, interfering influences, effects of structure, and the selection of experimental techniques. Focusing primarily on the single reaction of the Stille reaction, they provide comprehensive coverage of: Experimental conditions and selecting optimal experimental parameters Traditional and recently developed experimental procedures Side reactions and techniques for avoiding them Documented reactions-33 tables list 570 reactions, complete withconditions, yields, structures of major products, and common failures Easy-to-follow recipes for casual users of the Stille reaction The Stille Reaction is an indispensable working resource for all synthetic organic chemists, especially medicinal chemists. It is also an excellent graduate-level text for students of organic and medicinal chemistry. Bookseller Inventory # AAV9780471312734

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Book Description 1998. Paperback. Book Condition: New. 1st. 154mm x 31mm x 231mm. Paperback. A guide to making optimal use of one of the most important tools available to today's synthetic organic chemist Compatible with virtually all functional groups without protection and capab.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 672 pages. 0.871. Bookseller Inventory # 9780471312734

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