Organic Conformational Analysis and Stereochemistry from Circular Dichroism

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9780471354055: Organic Conformational Analysis and Stereochemistry from Circular Dichroism
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A unique guide to variable temperature CD spectroscopy and itsapplication in organic chemistry
This timely, original, thought-provoking work looks at organicstereochemistry from the perspective of circular dichroism (CD),using variable temperature CD spectroscopy to determine theconformation or absolute configuration of chiral molecules. With anemphasis on the analysis of optically active ketones and thecarbonyl chromophore, the authors demonstrate the advantages ofthis highly sensitive spectroscopic tool for obtainingstereochemical information in diverse areas of organic chemistry,biochemistry, and medicinal/pharmaceutical chemistry. They combinedetailed examples of stereochemical analysis with clear, thoroughpresentations, correlating chiroptical data with molecularmechanics calculations as well as data from NMR spectroscopy andother spectroscopic techniques. In addition, they provide asystematic survey of the professional literature, featuring anextraordinary collection of original CD spectra run at varyingtemperatures. Coverage includes:
* Chiroptical measurements: CD and ORD (Optical RotatoryDispersion)
* Conformational analysis of compounds ranging from simple cyclicketones to polycyclics
* Conjugated and homoconjugated systems
* Stereochemistry of the carbon-carbon double bond
* Stereochemistry from exciton coupling of two or morechromophores
* An interesting historical account of the development ofstereochemical concepts

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About the Author:

DAVID A. LIGHTNER, PhD, is R. C. Fuson Professor of Chemistry atthe University of Nevada, Reno.
JEROME E. GURST, PhD, is Professor of Chemistry at the Universityof West Florida, Pensacola.

Review:

"I feel that this book will form a valuable source to all thoseinterested in stereochemistry and conformational analysis of smallmolecules. This book will very useful..." (Talanta, Vol 53,2001)

"It is a must for libraries and for all research groups engaged inexperimental or theoretical work in this area." (Angewandte ChemieInternational Edition, Vol. 40 No. 9)

"...strongly recommended for research libraries serving organic andpharmaceutical chemists and...to some individuals working in thoseareas." (Journal of the American Chemical Society, Vol. 124, No.12, 2002)

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Book Description John Wiley and Sons Ltd, United States, 2000. Hardback. Condition: New. New. Language: English . Brand New Book. A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics Conjugated and homoconjugated systems Stereochemistry of the carbon-carbon double bond Stereochemistry from exciton coupling of two or more chromophores An interesting historical account of the development of stereochemical concepts. Seller Inventory # AAH9780471354055

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Book Description John Wiley and Sons Ltd, United States, 2000. Hardback. Condition: New. New. Language: English . Brand New Book. A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics Conjugated and homoconjugated systems Stereochemistry of the carbon-carbon double bond Stereochemistry from exciton coupling of two or more chromophores An interesting historical account of the development of stereochemical concepts. Seller Inventory # AAH9780471354055

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Book Description John Wiley and Sons Ltd, United States, 2000. Hardback. Condition: New. New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics Conjugated and homoconjugated systems Stereochemistry of the carbon-carbon double bond Stereochemistry from exciton coupling of two or more chromophores An interesting historical account of the development of stereochemical concepts. Seller Inventory # LIE9780471354055

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