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Synopsis
Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.
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Book Description
Developmental programming is a rapidly advancing discipline of great importance to scientists and health professionals. This unique text integrates contributions from world experts in placentology into the discipline of developmental programming, integrating animal research with human clinical and epidemiological data. Essential reading for researchers in placental biology and developmental programming.
About the Author
Graham J. Burton is Professor of Reproductive Biology and Director of the Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
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- PublisherCambridge University Press
- Publication date2011
- ISBN 10 052119945X
- ISBN 13 9780521199452
- BindingHardcover
- LanguageEnglish
- Number of pages258
- EditorBurton Graham J., Barker David J. P., Moffett Ashley, Thornburg Kent
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