Naloxone, Flumazenil and Dantrolene as Antidotes (International Programme on Chemical Safety: Evaluation of Antidotes)

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9780521454599: Naloxone, Flumazenil and Dantrolene as Antidotes (International Programme on Chemical Safety: Evaluation of Antidotes)
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The first volume provides an introduction to the series and reviews three antidotes: naloxone, a specific opioid antagonist used in the treatment of opiate poisoning; flumazenil, used to reverse the sedative, anti-convulsant and muscle-relaxant effects of benzodiazepines; and dantrolene sodium, used in the treatment of malignant hyperpyrexia and hyperthermia, neuroleptic malignant syndrome and hypercatabolic syndrome. This important new series arises from a coordinated programme of the International Programme on Chemical Safety (IPCS) (ILO/UNEP/WHO) and the Commission of the European Communities (CEC) to evaluate the efficacy of and indications for clinical and field use of these antidotes and other agents to treat poisoning.

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The first volume provides an introduction to the series and reviews three antidotes: naloxone, a specific opioid antagonist used in the treatment of opiate poisoning; flumazenil, used to reverse the sedative, anti-convulsant and muscle-relaxant effects of benzodiazepines; and dantrolene sodium, used in the treatment of malignant hyperpyrexia and hyperthermia, neuroleptic malignant syndrome and hypercatabolic syndrome.

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T. J. Meredith (Editor), D. Jacobsen (Editor), J. A. Haines (Editor), J. C. Berger (Editor)
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