Ion Channels: Molecules in Action

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9780521498821: Ion Channels: Molecules in Action

Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.

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Book Description:

Ion channels are crucial components of living cells. This overview of ion channel study includes up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction.

Review:

"...[a] clear and concise introduction to the physics, chemistry, and molecular biology used for ion channel research...what distinguishes this book from standard textbooks is the inclusion of some details of the experimental design, so as to allow the reader to have a better feel of how the studies were done and how the abstract theories emerged from the data...The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell

"...this book takes the reader to the frontiers of current research and should be of considerable interest to reproductive and developmental biologists." Ralph B.L. Gwatkin, Molecular Reproduction and Development

"The new Ion Channels book by David J. Aidley and Peter R. Stanfield offers an easy and smooth initiation....The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell

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Aidley, David J.; Stanfield, Peter R.
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Book Description CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 1996. Paperback. Book Condition: New. New. Language: English . Brand New Book ***** Print on Demand *****. Ion channels are crucial components of living cells. Situated in the cell s membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly. Bookseller Inventory # AAV9780521498821

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