Label-Free Biosensors - Softcover

Softcover

ISBN 10: 0521711517 ISBN 13: 9780521711517

Publisher: Cambridge University Press, 2009

Synopsis

Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack of knowledge of the best methods for using label-free assays to screen for biologically active molecules and accurately and precisely characterize molecular recognition events. This book reviews both established and newer label-free techniques and is intended to give both the expert user and the general reader interested in the technologies and applications behind label-free an insight into the field from expert opinion leaders and practitioners of the technologies. Most importantly, chapters contain worked examples from leaders in the field that take the reader through the basics of experimental design, setup, assay development, and data analysis.

About this title

Book Description

Techniques that analyze biologically active molecules and help scientists and researchers understand how molecules interact are becoming increasingly popular, with many thousands of instruments now installed worldwide. These techniques are often called "label-free," as they do not need a label on a molecule (such as radioactivity or fluorescence) to work. This book provides both a detailed technical review of label-free techniques and detailed worked examples that take the reader through the basics of setting up assays and analyzing data to help the reader get the most out of these new technologies.

About the Author

Dr Matthew A. Cooper is Founder and Managing Director of Cambridge Medical Innovations and Co-Founder and Chief Scientific Officer of Akubio. Dr Cooper is consulted widely for biosensor, biotechnology, and pharmaceutical companies in the UK, Europe, and the United States. He is a review panel member for BBSRC, EPSRC, US NIH, US NIAID, and Science Foundation Ireland and a Fellow of the Royal Society of Medicine.

Edition details

• Publisher: Cambridge University Press
• Publication date: 2009
• ISBN 10: 0521711517
• ISBN 13: 9780521711517
• Binding: Paperback
• Language: English
• Number of pages: 318
• Editor: Cooper Matthew A.