In 1986 epidemiologist Dr. David Snowdon embarked on a revolutionary scientific study that would forever change the way we view aging and old age. Dubbed the "Nun Study" because it involves a unique population of 678 Catholic sisters, this remarkable long-term research project remains today at the forefront of some of the world's most significant research on aging.
This remarkable book by one of the world's leading experts on Alzheimer's disease combines fascinating high-tech research on the brain with the heartfelt story of the aging nuns who are teaching scientists how we grow old — and how we can do so with grace. The Nun Study's findings are already helping scientists unlock the secrets to living a longer, healthier life.
Yet Aging With Grace is more than a groundbreaking health and hard-science book. It is the story of an altar boy who grew up to be a scientist studying the effects of aging on nuns. It is the poignant and inspiring stories of the nuns themselves. Ranging in age from 75 to 104, these remarkable women have allowed Dr. Snowdon access to their medical and personal records — and they have agreed to donate their brains upon death.
In Aging With Grace, we accompany Dr. Snowdon on his loving visits to nuns like Sister Clarissa, who at the age of 90 drives around the convent in a motorized cart she calls her "Chevy" and knows as much about baseball as any die-hard fan a third her age.
Then there is 104-year-old Sister Matthia, who until her death in 1998 knitted two pairs of mittens a day and prayed every evening for each of the four thousand students she taught over the years. These bright, articulate, and altruistic women have much to teach us about how faith, wisdom, and spirituality can influence the length and quality of our lives.
We also follow Dr. Snowdon into the lab as he and his colleagues race to decode one of the most devastating diseases known to humanity. We discover:
* Why high linguistic ability in early life seems to protect against Alzheimer's
* Which ordinary foods in the diet defend the brain against aging
* Why preventing strokes and depression is key to avoiding dementia
* Why it's never too late to start an exercise program
* What role heredity plays, and how lifestyle can increase our chances for a mentally vital old age
* How intangibles like community and faith help us age with grace
Both cutting-edge science and a personal prescription for hope, Aging With Grace shows how old age doesn't have to mean an inevitable slide into illness and disability; rather, it can be a time of promise and productivity, intellectual and spiritual vigor, and continuing freedom from disease.
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Dr. David Snowdon received his Ph.D. in epidemiology from the University of Minnesota and began the Nun Study there in 1986. In 1990 he moved the Nun Study to the Sanders-Brown Center on Aging at the University of Kentucky Medical Center, where he is also Professor of Neurology. One of the world's leading experts on Alzheimer's disease, he has presented his findings at scientific conferences throughout North America and Europe and has been published in such major medical journals as The Journal of the American Medical Association and The Journal of Gerontology.
"What distinguishes this study is Snowdon's decision not to maintain the usual "objective" distance from his subjects but rather to become emotionally involved with them. His commitment to treat them with 'care and respect' is readily apparent in the many warm and sympathetic anecdotes and his expression of deeply felt grief when any of the sisters becomes incapacitated by Alzheimer's or dies. ... [R]eaders will certainly appreciate the early insights to be gleaned from Snowdon's human- (rather than statistic-) centered and compassionate story."
— Publishers Weekly
"The Nun Study represents an absolutely unique American treasure and resource for all of us. The gems that Dr. Snowdon and his colleagues have unearthed will not only change the way you look at yourself and the aging people around you, they'll serve as catalysts for aging research for many years to come."
— Ronald Petersen, Ph.D., M.D., Director of the Alzheimer's Disease Research Center, Mayo Clinic
"There are lessons for all of us in this moving account of the School Sisters of Notre Dame and their commitment to help us find the causes of Alzheimer's disease. I came away with a new respect for the power of faith as well as the beauty and complexity of the human brain."
— Virginia M. Bell, M.S.W., co-author of The Best Friends Approach to Alzheimer's Care
"David Snowdon leads us through the enthralling scientific, but also very personal journey that he has been taking with the School Sisters of Notre Dame. The revelations along the way show us there is so much we can all do to alter for the better how we age, and ultimately how long we live. It is a journey not to be missed!"
— Thomas Perls M.D., M.P.H., Professor of Medicine, Harvard Medical School
"A beautiful story. Families will find hope and support through the commitment of the sisters who have dedicated their lives to helping others enjoy the gift of life as long as possible."
— Sigmund Tomkalski, Executive Director, Southeastern Wisconsin Chapter, Alzheimer's Association
emiologist Dr. David Snowdon embarked on a revolutionary scientific study that would forever change the way we view aging and old age. Dubbed the "Nun Study" because it involves a unique population of 678 Catholic sisters, this remarkable long-term research project remains today at the forefront of some of the world's most significant research on aging.<br><br>This remarkable book by one of the world's leading experts on Alzheimer's disease combines fascinating high-tech research on the brain with the heartfelt story of the aging nuns who are teaching scientists how we grow old ― and how we can do so with grace. The Nun Study's findings are already helping scientists unlock the secrets to living a longer, healthier life.<br><br>Yet <b>Aging With Grace</b> is more than a groundbreaking health and hard-science book. It is the story of an altar boy who grew up to be a scientist studying the effects of aging on nuns. It is the poignant and inspiring stories of the nuns th
Since 1986, the author, an epidemiologist, has directed a research project dubbed the Nun Study. According to Snowdon, who previously studied Seventh-Day Adventists, religious group members make ideal subjects because of their similar and somewhat insular lives. Specifically, he has been tracking the lives of 678 elderly nuns who are members of the School Sisters of Notre Dame, to assess the effects of aging. Snowdon describes in detail a pilot study he conducted with the sisters in Mankato, Wis., on the link between level of education and disabilities related to aging. This initial research convinced him to expand his base to other convents and to focus primarily on Alzheimer's disease. The participants, ranging in age from 75 to 104, agreed to provide access to their medical and personal histories and, after death, to donate their brain tissue to the project. What distinguishes this study is Snowdon's decision not to maintain the usual "objective" distance from his subjects but rather to become emotionally involved with them. His commitment to treat them with "care and respect" is readily apparent in the many warm and sympathetic anecdotes and his expression of deeply felt grief when any of the sisters becomes incapacitated by Alzheimer's or dies. Among the project's findings is a clear correlation between a low rate of Alzheimer's and high linguistic ability. Snowdon has also found a positive relationship between the consumption of certain antioxidants (e.g., lycopene, found in pink grapefruit, tomatoes and watermelon), an exercise program and an optimistic outlook and aging successfully. Although the study is still under way, readers will certainly appreciate the early insights to be gleaned from Snowdon's human- (rather than statistic-) centered and compassionate story.
Copyright 2001 Cahners Business Information, Inc.
The Road to Good Counsel Hill
They will open up to you, but only if you give of yourself first.
-- Sister Carmen Burg
On a spring morning in 1986, when the midwestern snowpack finally had begun to melt and the change of seasons encouraged new ideas to sprout, I sat nervously in the reception room of a convent in St. Paul, Minnesota, with a new idea of my own. I had come here to meet Sister Carmen Burg, who would either help my idea take root or wish me luck and send me on my way. I feared that she had bad news for me.
As an assistant professor of epidemiology at the University of Minnesota, I was struggling mightily to find my niche. In the competitive world of scientific research, especially at a large institution, I knew I had little time to establish my value to the department. All too frequently I remembered my chairman's words: "It's nice to be independent, but you must be funded."
Sister Carmen was an elected leader of one of Minnesota's largest groups of Catholic nuns, the School Sisters of Notre Dame. Nearly two hundred sisters lived at the Good Counsel Hill convent in Mankato, ninety miles southwest of St. Paul. I had contacted Sister Carmen to propose a research project involving the nuns. Now I worried that she had offered to meet me here -- before I ever got to Mankato -- so that it would be less awkward to turn me down. Underscoring my anxiety were images that had been seared into my memory at Sacred Heart elementary school. Most of the sisters had been serious, take-no-prisoners disciplinarians.
I had learned what I knew about the School Sisters of Notre Dame from Nora Keenan, a graduate student in our department. Nora had an unusual background for an epidemiologist: She had previously been one of the Notre Dames and had lived at the Mankato convent. She explained to me that her former congregation had originated in Bavaria in 1833, at a time of great political and social upheaval. The founder was a teacher at a parochial school, Caroline Gerhardinger, who later took the religious name Mary Teresa of Jesus. Mother Teresa, as she was known, believed that society could be transformed through the family, and that her call was to provide education and spiritual formation for girls -- particularly poor girls in rural areas. Shortly after the congregation was established, millions of Germans -- driven by crop failure and revolution -- began to emigrate to the United States, and the American bishops asked Mother Teresa to consider a new frontier for her mission. Together with four other sisters, she arrived at a forest settlement in Pennsylvania in 1847. From there, the congregation had moved west and south with the immigrants, founding schools and convents throughout North America. By 1986, the congregation (now based in Rome) had more than seven thousand sisters in nearly thirty countries. The Mankato convent -- one of seven provincial motherhouses in this country -- had been established in 1912.
Nora's account immediately sparked my interest. As I told her one day over lunch, I had built my career so far around studying unique populations of religious groups. For my Ph.D. thesis at Minnesota, I had joined an ongoing study of the Lutheran Brotherhood and investigated whether cancer and heart disease had any links to alcohol use. I then worked at California's Loma Linda Medical College, investigating the impact of diet on the health of Seventh-day Adventists. Now that I was back at Minnesota, I wanted to study aging and health, and I suspected that nuns or priests -- I did not really have a preference -- would offer unique clues. It was then that Nora had offered an introduction to Sister Carmen.
My nervous wait ended when a short, smiling woman came into the reception room and held out her hand. Sister Carmen was dressed in a simple white blouse, camel-colored cardigan, and long plaid skirt. Only a small pin over her heart signaled her membership in the School Sisters of Notre Dame. I had forgotten that since my days at Sacred Heart school, the reforms of the Second Vatican Council (or Vatican II) had made the black-and-white habit an option. Now in her early sixties, Sister Carmen wore large glasses, and behind them I could see the intelligent, patient eyes of a woman who had taught thousands of children. After we had chatted for a few minutes, she got right to the point.
"You know, Dr. Snowdon," she said in her distinct midwestern accent, "I love being a nun. Sisters are as human as the next person. But my question is, why on earth do you want to study nuns?"
She listened attentively as I described my past work with Lutherans and Adventists. I explained to Sister Carmen that these religious groups kept extensive membership lists and historical records that made them ideal subjects for epidemiological studies. And the members often had similar lifestyles, which enabled researchers to make powerful comparisons of factors connected to illness or health. Nuns had even more similar histories. They do not smoke. They are celibate. They have similar jobs and income, and they receive similar health care for most of their lives. All of these factors reduce the confounding variables -- such as poverty and lack of health care -- that can cloud the meaning of data. Outside a laboratory, it would be hard to find as pure an environment for research.
In fact, I went on, nuns had already played a crucial role in expanding our understanding of two devastating diseases that afflict women: breast cancer and cervical cancer. In the 1950s scientists observed that nuns had an unusually high risk for breast cancer. This led researchers to examine overall breast cancer rates more closely, comparing single to married women. It emerged that single women, like nuns, also had a high risk of breast cancer. The variable turned out to be pregnancy and the hormonal changes it causes. Much of today's understanding of how hormones affect breast health had its origin in this research.
Several famous studies, on the other hand, have reported cervical cancer to be rare in nuns and common in prostitutes, I offered, immediately realizing how odd this must have sounded to Sister Carmen. In this case, it was a sexually transmitted virus that ultimately emerged as the link to cancer. "Again, it isn't difficult to make the connection," I added.
"No, it isn't," she agreed.
I gladly changed the subject to aging and the purpose of my visit. "I'm hoping the study of the School Sisters of Notre Dame will lead to some major clues about aging and disease," I said. "Ultimately, I want to increase our knowledge and help people live longer, better lives."
Sister Carmen brightened when she heard this. If she was bothered by the vagueness -- or vastness -- of what I was proposing, she didn't let on. She sat quietly for a minute.
"Let me tell you, Dr. Snowdon," she began. "We have always believed in the power of knowledge and ideas. A large part of our mission has always been teaching. Over ninety percent of our sisters have been teachers at one time. Some of our older sisters taught in towns that had no schools before they arrived.
"Our sisters have spent their entire adult lives trying to help other people in the community. Even in their retirement, they have a deep passion and drive to help others. I think they would see your study as a way to continue their lifelong mission of helping others, of educating others."
"Yes, I hope so," I said.
Sister Carmen paused again and then let out a big, contented sigh. "Okay," she said, as only a Minnesotan can.
"Okay?" I was confused. "You mean -- "
"Wait." She raised her open hand and stopped me in midsentence. "I'll move forward with your request, but you need to listen carefully to what I am about to say. No matter what you do, I want you to remember who these women are. They are real people. Very dear to us. They are holy people, too. I don't want you to treat them as research subjects. Get to know them. Understand that many of the older sisters were the teachers or mentors of the younger sisters, and we treat them with the care and respect they deserve. We will expect nothing less from you."
I was a little stunned by Sister Carmen's statement. My prior research projects had included tens of thousands of participants, and I knew them only through their medical records and the questionnaires they had filled out. All researchers are taught that scientific objectivity depends on keeping one's distance from the people one studies. I had no idea how I could fulfill her request, so I simply nodded and said, "I'll do my best."
Sister Carmen gave me this parting advice: "They will open up to you," she said, "but only if you give of yourself first."
If Sister Carmen had asked me how I became an epidemiologist, I would have had to answer, "Chickens."
Puberty took away my lithe frame, ruining my imagined future as a gymnast, so I needed something new to do after school. Unlike my two older brothers, I had little interest in football or baseball. Being a teen also meant that I badly wanted to be different from my brothers -- and everyone else. So I decided to take up a hobby my father had pursued when he was a child: raising chickens and selling their eggs. With his help, I built a couple of coops in our suburban backyard and bought some multicolored bantam chickens at a local farm.
Bantams are the most petite breed of poultry, and they only occasionally lay eggs, which also are quite small. When I realized that these miniature chickens would produce only miniature profits, I began to do my homework. I became a student of chickens.
I read every book in the library about chickens, requested every pamphlet on chicken farming available from the United States Department of Agriculture, and wrote every hatchery in the state asking for information on their chicks...
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