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One of the most difficult areas of toxicology is the extrapolation of results obtained from experimental animals to man. The common occurrence of species differences in a number of biological processes confounds this extapolation. The metabolism of pesticides, drugs and other foreign compounds is a very important determinant of their toxicological effects. An understanding of species differences in metabolism and the ability to predict or to study directly the metabolic fate of a pesticide in man therefore are of great value in the validation of animal models for man. This review is concerned with the factors affecting species differences in the metabolism of foreign compounds in experimental animals and man. Additionally, specific examples of the metabolism of pesticides, drugs and industrial chemicals in man are assessed and the approaches to the execution of metabolism studies in humans, proposed.
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Book Description Wiley-Blackwell, 1991. Condition: Very Good. 1st Edition. Former Library book. Great condition for a used book! Minimal wear. Seller Inventory # GRP69563692
Book Description Wiley & Sons, Incorporated, John. Hardcover. Condition: Good. A copy that has been read, but remains in clean condition. All pages are intact, and the cover is intact. The spine may show signs of wear. Pages can include limited notes and highlighting, and the copy can include previous owner inscriptions. An ex-library book and may have standard library stamps and/or stickers. At ThriftBooks, our motto is: Read More, Spend Less. Seller Inventory # G0632022566I3N10
Book Description Blackwell Scientific Publications, U.S.A., 1988. Hardcover. Condition: Very Good. 1st Edition. Contains owner stamps, but otherwise text is unmarked. Seller Inventory # 014814
Book Description Blackwell, 1988. Hardback. Condition: VERY GOOD. 1988. Blackwell. First. Hard Cover. Book- VG, integral colour boards. 11x7.5. 120pp. Many b/w illus. One of the most difficult areas of toxicology is the extrapolation of results obtained with experimental animals to man. This review is concerned with the factors affecting species differences in the metabolism of foreign compounds in experimental animals and man. Seller Inventory # 1158665
Book Description Blackwell Scientific, Oxford., 1988. Hardcover. Condition: As New. 8vo, hardcover. No dj. As new condition. Tiny nick to upper edge of spine, otherwise, no cover wear, contents crisp, clean. Review copy- reviewer's slip laid in. vi, 120 p., illus. Seller Inventory # 1111130.48
Book Description Wiley-Blackwell, 1991. Hardcover. Condition: Good. 1. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. May not contain Access Codes or Supplements. May be ex-library. Shipping & Handling by region. Buy with confidence, excellent customer service!. Seller Inventory # 0632022566