Heterocyclic Chemistry

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9780632054534: Heterocyclic Chemistry
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This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists all over the world.

Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry.

The fourth edition of Heterocyclic Chemistry retains its original aims and flavour, thus maintaining the principal objective of earlier editions - to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. In recognition of the level at which much heterocyclic chemistry is now normally taught, the authors have included more advanced material, making the book appropriate both for postgraduate taught courses and to postgraduate students. It is important to emphasise that the more advanced sections of the book make it an important reference work for chemists at all levels who are working with heterocyclic compounds in industry.

The preparation of the fourth edition has allowed the authors to review thoroughly the material included in earlier editions, to amend it in the light of new knowledge, and to include much recent work. For example, new sections deal with heterocyclic aspects of combinatorial chemistry, bioprocessing, and conducting polymers. In its more advanced sections, the book emphasises modern methods for the synthesis and chemical manipulation of heterocyclic compounds.

Essential teaching material in the early chapters aims to capture the essence of heterocyclic reactivity in concise resumes suitable either as introductions, or as revisions/summaries for examination preparation. These early chapters are followed by detailed, systematic discussions of the chemical reactivity of particular heterocyclic systems. Original references and references to reviews are given throughout the text. These are essential for postgraduate teaching and to research workers, but do not interfere with the readability of the text for undergraduate students. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions as an Appendix), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

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About the Author:

John Joule is Emeritus Professor in the School of Chemistry, The University of Manchester, UK

Keith Mills spent 25 years in the Medicinal Chemistry and Development Chemistry departments at GlaxoSmithKline, Stevenage, UK, and is now an independent consultant.

Review:

“Overall, this book is recommended as a text for undergraduate and more advanced students on this pervasive, important, and underappreciated topic in chemistry.”  (Journal of Chemical Education, 1 October 2012)

"The work seems most valuable as a resource for researchers in the area, especially the detailed discussions that classify specific reactions . . . recommended. Chemistry collections serving upper-division undergraduates and above." (Choice, 1 February 2011)

"The fifth edition is a high-quality book, which represents a very valuable and concise source of information about heterocyclic chemistry. In the covered topics the book provides as a textbook a new gold standard... Due to the modern aspects it will be a compulsory reading for synthetically oriented chemists working in the field of heterocyclic chemistry." (Synthesis, February 2011)

"This excellent book is well written, heavily referenced, and thoroughly indexed. Accordingly, it serves as both an instructional heterocyclic chemistry textbook and a portal to the primary synthetic chemistry literature." (Journal of Medicinal Chemistry, 2011)

"My favourite chapter is the organometallic chemistry that presents an up-to-date treatment of the topic and helps confirms a colleague's observation that ‘With today's techniques one can be convinced that a modern organic chemist can make any small molecule he or she desires.' I particularly like the treatment of the concatenation of five-membered ring systems, an increasingly important area in medicinal chemistry. This chapter proves a real ‘coup de grace'." (Reviews, December 2010)

“My recommendation is, even if you already have the 4th edition, to buy the latest version. At only £39.95 for the paperback version this is outstanding value for money.” (Organic Process Research & Development Journal, 2010)

"My favourite chapter is the organometallic chemistry that presents an up-to-date treatment of the topic and helps confirms a colleague's observation that ‘With today's techniques one can be convinced that a modern organic chemist can make any small molecule he or she desires.' I particularly like the treatment of the concatenation of five-membered ring systems, an increasingly important area in medicinal chemistry. This chapter proves a real ‘coup de grace'." (Reviews, December 2010)

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Other Popular Editions of the Same Title

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