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Synopsis
A leading neuroscientist argues that the peripheral nervous system, long understood to play a key role in regulating basic bodily functions, also signals the onset of illness.
The central nervous system, consisting of the brain and the spinal cord, has long been considered the command center of the body. Yet outside the central nervous system, an elaborate network of nerve cells and fibers extends throughout our bodies, transmitting messages between the brain and other organs. The peripheral nervous system, as it’s known, regulates such vital functions as heart rate, digestion, and perspiration and enables us to experience the barrage of sounds, tastes, smells, and other sensory information that surrounds us. But beyond these crucial roles, the peripheral nervous system might do even more: it might warn us of diseases in our future.
As Moses Chao argues in Periphery, from Parkinson’s disease to autism to dementia, many neurological conditions emerge not in the brain but rather within the peripheral nervous system, in the dense network of nerves that wrap around the gastrointestinal tract. What’s more, dysfunctions of the peripheral nervous system can signal the onset of disease decades before symptoms like tremor or memory loss occur. Fortunately, unlike nerves in the brain and spinal cord, peripheral nerves can heal and regenerate in response to injury and aging. The therapeutic implications are remarkable. Chao shows how, with a better understanding of the peripheral nervous system, we could not only predict and treat neurological diseases long before their onset, but possibly prevent them altogether.
Full of new ideas and bold interpretations of the latest data, Periphery opens exciting avenues for medical research while deepening our understanding of a crucial yet underappreciated biological system.
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About the Author
Moses V. Chao is Professor of Cell Biology, Physiology and Neuroscience, and Psychiatry at the NYU School of Medicine. A member of the National Academy of Sciences and past president of the Society for Neuroscience, he is a recipient of the Zenith Award from the Alzheimer’s Association, a Jacob Javits Neuroscience Investigator Award, and a Guggenheim Fellowship.
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Periphery: How Your Nervous System Predicts and Protects against Disease
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Harvard University Press, 2023
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Periphery: How Your Nervous System Predicts and Protects against Disease
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Hardcover. Condition: new. Hardcover. A leading neuroscientist argues that the peripheral nervous system, long understood to play a key role in regulating basic bodily functions, also signals the onset of illness.Millions of years ago, one of the first organisms-a deep-ocean worm-functioned without a brain. It detected the light around itself through a mesh of cells that enabled sensation, performing all manner of bodily functions through its peripheral nervous system. In humans, these sensory nerves and fibers regulate digestion, heart rate, perspiration, and other involuntary systems. And beyond these critical roles in our bodies, Moses Chao argues, the peripheral nervous system can also warn us about neurodegenerative disorders that may be in our futures.Periphery describes how the peripheral nervous system evolved to detect sensations-smells, sounds, and touch. The organs of the PNS prove to be an integral part of how we make sense of the world, packaging and transmitting information throughout the body to inform our cognition, attention, perception, and memory. But Chao contends that the peripheral nerves may do more than regulate and detect-they may also allow us to predict the onset of disease. Thorough investigation of historical findings, clinical cases, and contemporary research suggests that peripheral activities create markers of neurological and psychiatric conditions, including Parkinson's disease, autism, and dementia. These are bold claims, some of them speculative, but Chao marshals compelling evidence. With optimal clinical management and even potential treatment increasingly dependent on the earliest possible detection, his insights may prove invaluable to patients and clinicians.Full of new ideas and provocative interpretations of the latest data, Periphery opens exciting avenues for medical research while deepening our understanding of a crucial and little appreciated biological system, foundational to all animal life. Moses Chao argues that activity in the peripheral nervous system predicts the onset of neurological and psychiatric conditions such as Parkinsons disease, autism, and dementia. Responsible for regulating a range of involuntary bodily processes and for detecting smells, sounds, and touch, the peripheral system may also be a key to better health. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9780674972308
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Periphery
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Hardback. Condition: New. A leading neuroscientist argues that the peripheral nervous system, long understood to play a key role in regulating basic bodily functions, also signals the onset of illness.The central nervous system, consisting of the brain and the spinal cord, has long been considered the command center of the body. Yet outside the central nervous system, an elaborate network of nerve cells and fibers extends throughout our bodies, transmitting messages between the brain and other organs. The peripheral nervous system, as it's known, regulates such vital functions as heart rate, digestion, and perspiration and enables us to experience the barrage of sounds, tastes, smells, and other sensory information that surrounds us. But beyond these crucial roles, the peripheral nervous system might do even more: it might warn us of diseases in our future.As Moses Chao argues in Periphery, from Parkinson's disease to autism to dementia, many neurological conditions emerge not in the brain but rather within the peripheral nervous system, in the dense network of nerves that wrap around the gastrointestinal tract. What's more, dysfunctions of the peripheral nervous system can signal the onset of disease decades before symptoms like tremor or memory loss occur. Fortunately, unlike nerves in the brain and spinal cord, peripheral nerves can heal and regenerate in response to injury and aging. The therapeutic implications are remarkable. Chao shows how, with a better understanding of the peripheral nervous system, we could not only predict and treat neurological diseases long before their onset, but possibly prevent them altogether.Full of new ideas and bold interpretations of the latest data, Periphery opens exciting avenues for medical research while deepening our understanding of a crucial yet underappreciated biological system. Seller Inventory # LU-9780674972308
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Periphery
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ISBN 13: 9780674972308
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Periphery : How Your Nervous System Predicts and Protects Against Disease
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ISBN 13: 9780674972308
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