Parkinson's Disease (Advances in Neurology) - Hardcover

Hardcover

ISBN 10: 0781703417 ISBN 13: 9780781703413

Publisher: Lippincott Williams & Wilkins, 1995

Synopsis

This volume presents a comprehensive account of the latest basic and clinical research on Parkinson's disease. With contributions from more than 200 leading international investigators, the book covers the entire spectrum of current research on the epidemiology and genetics of Parkinson's disease, its biochemical and physiopathological aspects, its clinical features, and its treatment. A major portion of the book focuses on the etiologic and pathogenic mechanisms of Parkinson's disease, particularly the causes of nigrostriatal cell death and the impairment of various neurotransmitters. Included are studies on receptor mechanisms, the impairment of mitochondrial activity, and the role of oxidative stress, exogenous and endogenous toxins, and excitatory amino acids in neurodegeneration. Other contributors discuss recent progress in identifying neurotrophic factors of clinical significance in Parkinson's disease. Close attention is also given to functional neuroimaging studies using SPECT, PET, and MR imaging and spectroscopy. The final section examines new treatment strategies for Parkinson's disease and for the complications of chronic levodopa therapy.

About this edition

• Publisher: Lippincott Williams & Wilkins
• Publication date: 1995
• ISBN 10: 0781703417
• ISBN 13: 9780781703413
• Binding: Hardcover
• Number of pages: 612
• Editor: Battistin Leontino, Scarlato Guglielmo, Caraceni Tommaso, Ruggieri Stefano