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This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance the permeability, solubility, strength, and function of drug formulations, examine protein-protein exchanges and reactions, and calculate pKa values.
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...The most outstanding feature of the book is that this book outlines the fascinating possibilities of the application of ACE....this volume not only simply commands a presence on every pharmaceutical bookshelf but also belongs in the library of everyone wishing to stay better informed.
-Current Engineering Practice
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