Lashley's Essentials of Clinical Genetics in Nursing Practice, Second Edition

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9780826129123: Lashley's Essentials of Clinical Genetics in Nursing Practice, Second Edition

Christine E. Kasper, PhD, RN, FAAN, FACSM

Tonya A. Schneidereith, PhD, CRNP, PPCNP-BC, CPNP-AC

Felissa R. Lashley, PhD, RN, FABMGG

Completely updated to help nurses learn to "think genetically"

Today's nurses must be able to "think genetically" to help individuals and families who are affected by genetic disease or contemplating genetic testing. This book is a classic resource for nursing students and practitioners at all levels who need to acquire the knowledge and skills for using genomics in their practice. This completely updated second edition encompasses the many recent advances in genetic research and knowledge, providing essential new information on the science, technology, and clinical application of genomics. It focuses on the provision of individualized patient care based on personal genetics and dispositions. The second edition is designed for use by advanced practice nursing programs, as well as undergraduate programs. It pinpoints new developments in prenatal, maternity, and pediatric issues and supplies new information on genomics-based personal drug therapy, environmental susceptibilities, genetic therapies, epigenetics, and ethics.

The text features a practical, clinically oriented framework in line with the core competencies defined by the AACN. It delivers information according to a life-span approach used in the practice setting. The second edition continues to provide basic information on genomics, its impact on health care, and genetic disorders. It covers prevention, genetic counseling and referral, neuropsychiatric nursing, and public health. The core of the text presents information on a variety of diseases that affect patients throughout the life span, with specific guidance on the nursing role. Also included are tests for a variety of diseases and information on pharmacogenomics, which enable health care providers to select the best drugs for treatment based on a patient's genetic makeup. Plentiful case study examples support the information throughout. Additionally, an instructor's package of PowerPoint slides and a test bank are provided.

New to the Second Edition:

  • Completely updated
  • Personal drug therapy based on genomics
  • Environmental susceptibilities
  • Prenatal detection and diagnosis
  • Newborns and genetic screening
  • Reproductive technologies
  • Ethical issues
  • Genetic therapies
  • Epigenetics
  • Includes content for graduate-level programs
  • PowerPoint slides and a test bank for all student levels

Key Features:

  • Encompasses state-of-the-art genomics from a nursing perspective
  • Provides a practical, clinically oriented life-span approach
  • Covers science, technology, and clinical application of genomics
  • Addresses prevention, genetic testing, and treatment methods

"synopsis" may belong to another edition of this title.

From the Back Cover:

Completely updated to help nurses learn to "think genetically"

Today's nurses must be able to "think genetically" to help individuals and families who are affected by genetic disease or contemplating genetic testing. This is a classic resource for nursing students and practitioners at all levels who need to acquire the knowledge and skills for using genomics in their practice. The completely updated second edition encompasses the many recent advances in genetic research and knowledge, providing essential new information on the science, technology, and clinical application of genomics. It focuses on the provision of individualized patient care based on personal genetics and dispositions. The second edition is designed for use by advanced practice nursing programs in addition to undergraduate programs. It pinpoints new developments in prenatal, maternity, and pediatric issues along with new information on genomics-based personal drug therapy, environmental susceptibilities, genetic therapies, epigenetics, and ethics

The text features a practical, clinically oriented framework in line with the core competencies defined by the AACN. It delivers information according to a lifespan approach used in the practice setting. The second edition continues to provide basic information on genomics, its impact on healthcare, and genetic disorders. It covers prevention, genetic counseling and referral, neuropsychiatric nursing, and public health. The core of the text presents information on a variety of diseases that affect patients throughout the lifespan, with specific guidance for the nursing role. Also included are tests for a variety of diseases and information on pharmacogenomics, which enables healthcare providers to select the best drugs for treatment based on a patient's genetic makeup. Plentiful case examples support the information throughout. Additionally, an instructor's package of PowerPoint slides and a test bank is provided for both the graduate and undergraduate levels.

New to the Second Edition:

Completely updated with several new chapters

Personal drug therapy based on genomics

Environmental susceptibilities

Prenatal detection and diagnosis

Newborn and genetic screening

Reproductive technologies

Ethical issues

Genetic therapies

Epigenetics

Content for graduate-level programs

PowerPoint slides and test bank for all student levels

Key Features:

Encompasses state-of-the-art genomics from a nursing perspective

Provides a practical, clinically-oriented lifespan approach

Covers science, technology, and clinical application of genomics

Addresses prevention, genetic testing, and treatment methods

Written for undergraduate and graduate level nursing students

About the Author:

Christine E. Kasper, PhD, RN, FAAN, FACSM, is a senior research scientist and professor at the U.S. Department of Veterans Affairs and Uniformed Services University of the Health Sciences. Prior to that, she held the Adelaide M. Nutting Endowed Research Chair at the Johns Hopkins School of Nursing and was also a faculty member at the University of California—Los Angeles and the University of Wisconsin—Madison. Dr. Kasper received her BSN from the University of Evansville, her MSN from Rush University, and her PhD from the University of Michigan.

Dr. Kasper has published more than 110 research papers, book chapters, reviews, and editorials in highly respected nursing and scientific journals. She was the founding editor of Biological Research for Nursing and is the current editor of the Annual Review of Nursing Research. She was a co-author of the ground-breaking book, In Search of Nursing Science, used in many nursing programs as a philosophy of science text. Her research has included funding from the National Institutes of Health (NIH), the National Aeronautics and Space Administration (NASA), and the Department of Veterans Affairs as the principal investigator on 10 grants. Additionally, she has received funding for 11 studies from foundations and universities, and has participated as a co-investigator on 14 additional interdisciplinary grants ranging from clinical genomics in nursing practice to genotoxic changes arising from embedded military-relevant heavy metals.

Dr. Kasper has been inducted as a fellow of the American Academy of Nursing and the American College of Sports Medicine. In 2015, she received the distinctive honor of becoming an inductee of the Sigma Theta Tau International Nurse Researcher Hall of Fame.



Tonya A. Schneidereith, PhD, CRNP, PPCNP-BC, CPNP-AC, is an assistant professor of nursing at Stevenson University. Dr. Schneidereith received her BSN from Florida State University, her MSN from the University of Pennsylvania, and her PhD from the Johns Hopkins University. While at Johns Hopkins, she studied under the direction of Dr. Christine Kasper, Dr. Gayle Page, Dr. Kirby Smith, and Dr. George Dover on the pharmacogenetics of fetal hemoglobin and F-cell variation. She was a summer intramural research assistant at the National Human Genome Research Institute under the direction of Dr. Wendy Fibison and has received funding as the primary investigator from the National Institute of Nursing Research for her work in molecular genetics.

Among her national and international presentations, Dr. Schneidereith has published in the Annual Review of Nursing Research, Experimental Hematology, and Human Molecular Genetics. She also serves as a reviewer for the Journal of Nursing Education and Nursing Education Perspectives.

Additionally, Dr. Schneidereith maintains a clinical practice as a pediatric nurse practitioner, with over two decades of experience in pediatric acute and primary care.



Felissa R. Lashley, PhD, RN, FABMGG, is former dean and professor at the College of Nursing at Rutgers, The State University of New Jersey. Prior to that, she was a dean and professor at the Southern Illinois University—Edwardsville and a clinical professor of pediatrics at the School of Medicine, Southern Illinois University—Springfield. She is the first nurse to be certified as a PhD medical geneticist by the American Board of Medical Genetics, and is a founding fellow of the American College of Medical Genetics. She began her practice of genetic evaluation and counseling in 1973.

"About this title" may belong to another edition of this title.

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