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Akin to nitric oxide, carbon monoxide (CO) was initially viewed as a pure toxic gas, yet it has been recently demonstrated to be an important endogenous molecule of gas that has profound physiological and pathophysiological effects on the cardiovascular system. In spite of the growing understanding achieved in this field, until now a comprehensive book summarizing the extraordinary advances in the research of the cardiovascular effects of CO has not been available.
Carbon Monoxide and Cardiovascular Functions responds to the vexing challenges and exciting opportunities that confront researchers and clinicians studying the biological roles of CO in the cardiovascular system. This book presents many never-before-published results including the first case of human CO deficiency. It also discusses disorders where the cardiovascular effects of CO might have been altered, including hypertension, diabetes, stroke, and ischemic heart damage.
A product of the collected knowledge of internationally respected scientists, this book serves as a standard reference summarizing recent developments, scientific controversies, and future directions in the study of the biological actions of CO on the cardiovascular system. By covering both ancient and state-of-the-art methodologies in great detail, Carbon Monoxide and Cardiovascular Functions, affords a rapid mastery of the powerful new advances in CO study.
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The book gives a first rate summary of the mechanisms by which CO exerts its action on vascular smooth muscle...The illustrations and pertinent data are well organized and clear. The book is a good source for graduate or upper division undergraduate courses in pharmacology, physiology, or biochemistry of CO. To my knowledge there are no other books in this subject. 3 stars.
- John Buchholz, Ph.D., Loma Linda University, Doody's Notes
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