Key Developments for Faster, More Precise Detection Capabilities
Driven by the demand for the rapid and advanced detection of explosives, chemical and biological warfare agents, and narcotics, ion mobility spectrometry (IMS) undergone significant refinements in technology, computational capabilities, and understanding of the principles of gas phase ion chemistry and mobility. Beginning with a thorough discussion of the fundamental theories and physics of ion mobility, Ion Mobility Spectrometry, Second Edition describes the recent advances in instrumentation and newly pioneered applications.
Divided into three sections, the first presents a history of technological developments, basic principles, theories, and other factors that govern the response in IMS. The second section describes aspects of IMS technology including sample introduction methods, draft tubes, modern methods for data analysis and display, the combination of mobility spectrometers with chromatographic methods, miniaturized IMS sensors, alternative ionization sources, and advances in computational capabilities that improved the acquisition and treatment of data. The final section emphasizes rapidly developing and exciting applications of IMS. The section is subdivided into existing, proven and potential applications encompassing the traditional forensic, military, and counter-terrorism applications and the now well-developed methods for detect biological agents and characterizing bio-molecules. It also highlights other applications found in clinical and environmental venues and await further development.
This new edition of Ion Mobility Spectrometry offers a lucid and complete analysis of the technological and contextual developments surrounding the chemistry, instrumentation and growing number of applications of IMS that incorporate and depend upon the latest innovations in the field.
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G.A. Eiceman is a professor at New Mexico University in Las Cruces.
Z. Karpas is an associate at the Nuclear Research Center in Beer-Shev, Israel.
Herbert H. Hill is a professor at Washington State University in Pullman.
"... an excellent book and essential for every researcher and engineer working in the field of ion mobility. The authors, who are leading experts in IMS technology, provide an excellent overview of the current state of science and technology related to IMS and the most recent developments in this field. ... well written and easily understandable, with a well-balanced mix of practice-oriented information and theoretical background knowledge."
―Thomas Mayer, Department of Monitoring and Exploration Technologies, Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany, from International Journal for Ion Mobility Spectrometry, December 2014
Praise for the Previous Edition
"... The second edition of this book provides a timely update to the fundamental theory, advancements in instrumentation, and the development of new applications of IMS.... The book accomplishes the objectives outlined by the authors... The CD [is] a useful and practical addition to this book... Overall, this book should be useful to experts in IMS research as well as those new to the technology. As a practical book, it offers a well-balanced combination of theory and application... I highly recommend it to anyone interested in IMS."
―Robert G. Ewing, New Mexico Institute of Mining and Technology, in JACS, Vol. 128, 2006
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