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Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations. There has been no comprehensive book on this subject for more than a decade. This book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans. Contents include: Chemistry and mode of action; pharmacology, toxicology and efficacy; use in large and small animals and in humans; and resistance against MLs.
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J. Vercruysse, Faculty of Veterinary Medicine, Ghent University. R. S. Rew, Pfizer Inc..Review:
"It provides a comprehensive and detailed review of the field (the first for over 10 years) and will be a valuable reference source." (Parasitology)
"This is an excellent book and invaluable reference source to all those involved in parasite control throughout the world." (The Veterinary Journal)
"It will make an excellent addition to researchers’ personal libraries but also to the libraries of pharmacological, veterinary and medical research and teaching organizations. This is an excellent informative book on this important class of compounds." (Tropical Animal Health & Production)
"In this modern, well-written book the authors have made accessible the recent knowledge on macrocyclic lactone anthelmintics. This publication will be of interest to parasitologists, pharmacologists and researchers working in veterinary and human medicine." (Helminthologia)
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