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Synopsis
Portraying the many scientists involved, this volume chronicles the race to create the first artificial human gene and the first commercial application of genetic-engineering techniques--the synthesis of human insulin
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Reviews
Drawing on scores of interviews with participants, science writer Hall describes the 19761978 "race"begun when the pharmaceutical giant Eli Lilly organized a recombinant DNA symposium of scientists in Indianapolisbetween a Harvard biogenetics lab, headed by scientist Walter Gilbert, and two San Franciscoarea labs, one calling itself City of Hope (eventually funded by a tiny company called Genentech) and the other a William Rutter-Howard Goodman team ultimately backed by Eli Lilly. The goal: to make insulin in mass-market quantities by using recombinant DNA techniquessplicing a human gene with bacteria. This is demanding reading for biochemistry novices, but the drama is double-track: scientists plus entrepreneurs. In late 1978, the City of Hope team won out ("the bacteria went bonkers"), while the unlucky Harvard/Biogen lab found gremlins in its "soup." A new era of Big Buck science? The jury is still out. First serial to California magazine.
Copyright 1987 Reed Business Information, Inc.
During the later 1970s research on recombinant DNA and bacterial cloning of human genes was at the center of "Big Amazing Science." Recognition by peers, Nobel prizes, and lucrative pharmaceutical contracts drove ambitious scientists in a feverish competition, and two major biotechnology firms emergedBiogen and Genentech. Through interviews with the participants, Hall has assembled a story of science at the cutting edge, and especially of the personalities involvedtheir motivations, their philosophies. While the cloning of human insulin and somatostasin has established Genentech as a near billion dollar enterprise, the commercial and social impact of this research is yet to be determined. To be read for the human interest side of the story. Walter P. Coombs, Jr. Biology Dept., Western New England Coll., Springfield, Mass.
Copyright 1987 Reed Business Information, Inc.
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Invisible Frontiers : The Race to Synthesize the Human Gene
Published by
Grove/Atlantic, Incorporated, 1987
ISBN 10: 0871131471
ISBN 13: 9780871131478
Used
Hardcover
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Condition: Good. Former library book; may include library markings. Used book that is in clean, average condition without any missing pages. Seller Inventory # 2567724-75
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Invisible Frontiers : The Race to Synthesize the Human Gene
Published by
Grove/Atlantic, Incorporated, 1987
ISBN 10: 0871131471
ISBN 13: 9780871131478
Used
Hardcover
Seller: Better World Books, Mishawaka, IN, U.S.A.
Seller rating 5 out of 5 stars
Condition: Good. Used book that is in clean, average condition without any missing pages. Seller Inventory # 4608093-6
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Invisible Frontiers: The Race to Synthesize a Human Gene
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Hardcover. Condition: Fair. No Jacket. Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less 1.15. Seller Inventory # G0871131471I5N00
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Invisible Frontiers: The Race to Synthesize a Human Gene
Published by
Atlantic Monthly Pr, 1987
ISBN 10: 0871131471
ISBN 13: 9780871131478
Used
Hardcover
First Edition
Seller: Black Tree Books, Davenport Center, NY, U.S.A.
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Hardcover. Condition: Fine. Dust Jacket Condition: Near Fine. 1st Edition. A fine copy in a near fine wrapper. Light sunning to spine side of real panel. Light overall shelf wear to a both bright and crisp wrapper. Internally unmarked and clean pages. A very clean edition. Seller Inventory # 5096
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Invisible Frontiers: The Race to Synthesize a Human Gene
Published by
Atlantic Monthly Press, 1981
ISBN 10: 0871131471
ISBN 13: 9780871131478
Used
Hardcover
First Edition
Seller: Sekkes Consultants, North Dighton, MA, U.S.A.
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Hardcover. Condition: Near Fine. Dust Jacket Condition: Near Fine. 1st Edition. Hall reconstructs the early days of the genetic engineering revolution. In the 1970s, the new recombinant DNA technology made conceivable the actual synthesis, from scratch, of a human gene. Three hotly competitive research groups at either end of the continent embarked on the project. One was directed by future Nobel laureate Walter Gilbert of Harvard. A second, at the University of California at San Francisco, was under William Rutter and Howard Goodman. A third at the City of Hope Research Center in Duarte, Calif., soon came under the corporate umbrella of a new biotechnology firm, Genentech, formed by another UCSF lab chief, Herb Boyer. Slightly slanted, small closed tear to the dust-jacket top of the spine. Prior owner name on ffep. First edition. 6¾" - 9¼". book. Seller Inventory # 277043
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Invisible Frontiers: The Race to Synthesize a Human Gene
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