Mechanics of Motor Proteins and the Cytoskeleton

3.91 avg rating
( 11 ratings by Goodreads )
 
9780878933334: Mechanics of Motor Proteins and the Cytoskeleton

Motor proteins are molecular machines that convert chemical energy from ATP hydrolysis into mechanical work, which powers cell motility. Over the last ten years, single-molecule techniques and structural studies have led to rapid progess in understanding how these biological motors operate. How do they move? How do they generate force? How much fuel do they consume, and with what efficiency? Mechanics of Motor Proteins and the Cytoskeleton brings these new findings together.

This book is for biology, physics, and engineering students who want to learn about the principles of protein mechanics and how it applies to the morphology and motility of cells. Understanding how motors and the cytoskeleton operate requires mechanical concepts such as force, elasticity, damping, and work. Introductory physics textbooks address these concepts, yet they are concerned primarily with macroscopic systems, whose motions are qualitatively different from the highly damped, diffusive motion of individual molecules.

Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centered on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.

The book assumes a rudimentary knowledge of cell biology as well as freshman physics, though all concepts are introduced from first principles, and numerous boxed examples and figures aid the non-mathematical reader. For the mathematically inclined, detailed proofs of important results are included in the Appendix.

"synopsis" may belong to another edition of this title.

About the Author:


Jonathon Howard is Eugene Higgins Professor of Molecular Biophysics and Biochemistry and Professor of Physics at the Yale School of Medicine. He earned a Ph.D. in Neurobiology at Australian National University, doing postdoctoral research there as well as at the University of Bristol and the University of California, San Francisco. The Howard Lab uses highly sensitive techniques to visualize and manipulate individual biological molecules, seeking to understand the interaction rules that allow molecules to work together to form highly organized and dynamic cellular structures.The writing of Mechanics of Motor Proteins and the Cytoskeleton was inspired by Dr. Howard's teaching of a course on Cell Motility at the University of Washington.

Review:


"The cytoskeleton is an area of intense research and we are in danger of drowning in a sea of facts. A textbook is needed which starts from first principles and leads to an understanding of the dynamics of the system. And here is that book."
--Edwin Taylor, Nature


"The book is a great launching point for gaining a biophysical understanding of the current detailed literature of motility which is increasingly filled with mathematical models describing motility data. As such, it will benefit students of a wide range of biological and physical backgrounds who are interested in understanding the nuts-and-bolts of cellular motility."
--Stephen J. King, Cell


"About this title" may belong to another edition of this title.

Buy New View Book
List Price: US$ 86.95
US$ 75.37

Convert Currency

Shipping: FREE
From United Kingdom to U.S.A.

Destination, Rates & Speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

1.

Jonathon Howard
Published by Sinauer Associates Inc.,U.S., United States (2001)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Paperback Quantity Available: 10
Seller:
The Book Depository US
(London, United Kingdom)
Rating
[?]

Book Description Sinauer Associates Inc.,U.S., United States, 2001. Paperback. Book Condition: New. New edition. Language: English . Brand New Book. Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together. Bookseller Inventory # SPR9780878933334

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 75.37
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

2.

HOWARD J
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Quantity Available: 5
Seller:
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Book Condition: New. New. US edition. Perfect condition. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-68846

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 75.38
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

3.

HOWARD J
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Quantity Available: 5
Seller:
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB68846

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 75.43
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

4.

HOWARD J
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Quantity Available: 5
Seller:
Basi6 International
(Irving, TX, U.S.A.)
Rating
[?]

Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-68846

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 78.78
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

5.

Jonathon Howard
Published by Sinauer Associates Inc.,U.S., United States (2001)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Paperback Quantity Available: 10
Seller:
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Sinauer Associates Inc.,U.S., United States, 2001. Paperback. Book Condition: New. New edition. Language: English . Brand New Book. Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together. Bookseller Inventory # SPR9780878933334

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 80.49
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

6.

Jonathon Howard
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Quantity Available: 1
Seller:
Majestic Books
(London, ,, United Kingdom)
Rating
[?]

Book Description Book Condition: New. Bookseller Inventory # 3467403

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 81.40
Convert Currency

Add to Basket

Shipping: US$ 7.37
From United Kingdom to U.S.A.
Destination, Rates & Speeds

7.

Jonathon Howard
Published by Sinauer Associates Inc.,U.S. 2005-12-06 (2005)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Quantity Available: 3
Seller:
Chiron Media
(Wallingford, United Kingdom)
Rating
[?]

Book Description Sinauer Associates Inc.,U.S. 2005-12-06, 2005. Book Condition: New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. Bookseller Inventory # NU-LBR-00652966

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 87.28
Convert Currency

Add to Basket

Shipping: US$ 4.01
From United Kingdom to U.S.A.
Destination, Rates & Speeds

8.

Howard, Jonathon
Published by Sinauer Associates is an impri (2001)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Paperback Quantity Available: 2
Seller:
Murray Media
(North Miami Beach, FL, U.S.A.)
Rating
[?]

Book Description Sinauer Associates is an impri, 2001. Paperback. Book Condition: New. Never used!. Bookseller Inventory # P110878933336

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 99.83
Convert Currency

Add to Basket

Shipping: US$ 1.99
Within U.S.A.
Destination, Rates & Speeds

9.

Howard, Jonathon
Published by Sinauer Associates is an impri (2001)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Paperback Quantity Available: 2
Seller:
Save With Sam
(North Miami, FL, U.S.A.)
Rating
[?]

Book Description Sinauer Associates is an impri, 2001. Paperback. Book Condition: New. Brand New!. Bookseller Inventory # VIB0878933336

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 99.83
Convert Currency

Add to Basket

Shipping: US$ 3.00
Within U.S.A.
Destination, Rates & Speeds

10.

Jonathon Howard
Published by Sinauer Associates Inc.,U.S., United States (2001)
ISBN 10: 0878933336 ISBN 13: 9780878933334
New Paperback Quantity Available: 10
Seller:
Book Depository hard to find
(London, United Kingdom)
Rating
[?]

Book Description Sinauer Associates Inc.,U.S., United States, 2001. Paperback. Book Condition: New. New edition. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together. Bookseller Inventory # BTE9780878933334

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 110.38
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book