Novel Anticancer Drug Protocols (Methods in Molecular Medicine)

0 avg rating
( 0 ratings by Goodreads )
 
9780896039636: Novel Anticancer Drug Protocols (Methods in Molecular Medicine)
View all copies of this ISBN edition:
 
 

We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy. Advances in cancer cell biology fueled by the molecular biology revolution have resulted in the uncovering of many novel potential molecular targets for cancer therapy. New anticancer drug discovery and development is now largely focused on exploiting these new molecular targets, which encompass oncogenes, tumor s- pressor genes, and their gene products, as well as targets involved in tumor angiogenesis, metastasis, survival, and longevity mechanisms. Exploitation of some of these targets has already yielded fruits and introduced new paradigms of molecularly targeted cancer therapy into the clinic, namely, protein kinase in- bition by antibodies or small molecules, exemplified by Herceptin® (trastuzumab), a humanized antibody targeted against the HER-2 growth factor receptor tyrosine kinase for the treatment of metastatic breast cancer; and Gleevec, a small molecule bcr-abl kinase inhibitor for the treatment of chronic myel- enous leukemia.

"synopsis" may belong to another edition of this title.

From the Back Cover:

With many potential molecular targets of anticancer agents already identified and many more yet to be discovered, the great challenges are now to successfully validate them, to devise relevant assays, and to translate the results into effective medicines for cancer patients. In Novel Anticancer Drug Protocols, expert basic researchers and clinicians from both industry and academia not only survey the whole arena of novel antitumor drug targets, but also present a wide-ranging selection of the key techniques currently being applied throughout anticancer drug discovery and development. Described in step-by-step detail to ensure successful results, these methods are employed in experiments involving such central topics as immunotherapy, angiogenesis, cancer metastasis, the cell cycle, signal transduction inhibitors, apoptosis, antibodies, antisense molecules, microarray gene expression analysis, flow cytometry, and PET imaging for cancer target validation. There are also proven methods for the preclinical identification of drug targets and for target validation during the clinical trials of novel agents. Each method provides background information, easy-to-follow instructions, notes on avoiding pitfalls, and alternative procedures.
Eminently practical and user-friendly, Novel Anticancer Drug Protocols offers all researchers involved in cancer drug development a blend of the critical preclinical and clinical assays needed for the target validation and discovery of novel agents today.

"About this title" may belong to another edition of this title.

Other Popular Editions of the Same Title

9781489938398: Novel Anticancer Drug Protocols (Methods in Molecular Medicine)

Featured Edition

ISBN 10:  1489938397 ISBN 13:  9781489938398
Publisher: Humana Press, 2013
Softcover

Top Search Results from the AbeBooks Marketplace

1.

Published by Humana Press
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 4
Seller:
Books Puddle
(New York, NY, U.S.A.)
Rating
[?]

Book Description Humana Press. Condition: New. pp. 372 1st Edition. Seller Inventory # 26250934

More information about this seller | Contact this seller

Buy New
US$ 23.28
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds

2.

Published by Humana Press
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 4
Seller:
Majestic Books
(London, ,, United Kingdom)
Rating
[?]

Book Description Humana Press. Condition: New. pp. 372. Seller Inventory # 7629801

More information about this seller | Contact this seller

Buy New
US$ 23.77
Convert currency

Add to Basket

Shipping: US$ 6.96
From United Kingdom to U.S.A.
Destination, rates & speeds

3.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New PAPERBACK Quantity Available: 10
Seller:
DC Bookdepot
(New Delhi, India)
Rating
[?]

Book Description PAPERBACK. Condition: new. Cover Image & ISBN may be different from US edition but contents as US Edition.NO CD AND ACCESS CODE. We may ship the books from Asian regions for inventory purpose. Printing in English language. We Do not Ship APO FPO AND PO BOX. Seller Inventory # 56582

More information about this seller | Contact this seller

Buy New
US$ 23.47
Convert currency

Add to Basket

Shipping: US$ 9.20
From India to U.S.A.
Destination, rates & speeds

4.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 5
Seller:
firstbookstore
(New Delhi, India)
Rating
[?]

Book Description Condition: Brand New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Seller Inventory # AINDN-3841

More information about this seller | Contact this seller

Buy New
US$ 34.45
Convert currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, rates & speeds

5.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 1
Seller:
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Condition: New. New. US edition. Perfect condition. Customer satisfaction our priority. Seller Inventory # ABE-OCT-117443

More information about this seller | Contact this seller

Buy New
US$ 34.65
Convert currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, rates & speeds

6.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 5
Seller:
Romtrade Corp.
(STERLING HEIGHTS, MI, U.S.A.)
Rating
[?]

Book Description Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship fro the US or other locations in India depending on your location and availability. Seller Inventory # AUNEW-3841

More information about this seller | Contact this seller

Buy New
US$ 34.69
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

7.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 1
Seller:
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Seller Inventory # SHUB117443

More information about this seller | Contact this seller

Buy New
US$ 34.70
Convert currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, rates & speeds

8.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 1
Seller:
Basi6 International
(Irving, TX, U.S.A.)
Rating
[?]

Book Description Condition: Brand New. New, US edition. Excellent Customer Service. Seller Inventory # ABEUSAOCT18-117443

More information about this seller | Contact this seller

Buy New
US$ 34.96
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

9.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 5
Seller:
PLYSH STORE
(South Delhi, DELHI, India)
Rating
[?]

Book Description Condition: Brand New. New Original Edition. Same ISBN as per description. Delivery within 4 - 5 days. Seller Inventory # 0896039633-1102018

More information about this seller | Contact this seller

Buy New
US$ 36.17
Convert currency

Add to Basket

Shipping: US$ 5.11
From India to U.S.A.
Destination, rates & speeds

10.

BUOLAMWINI JOHNK, ET AL
ISBN 10: 0896039633 ISBN 13: 9780896039636
New Quantity Available: 2
Seller:
University Bookstore
(DELHI, DELHI, India)
Rating
[?]

Book Description Condition: New. This is Brand NEW. Seller Inventory # Star-07122018-22759

More information about this seller | Contact this seller

Buy New
US$ 33.00
Convert currency

Add to Basket

Shipping: US$ 10.23
From India to U.S.A.
Destination, rates & speeds

There are more copies of this book

View all search results for this book