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This comprehensive reference for novice students and experienced scientists studying DNA in organisms compares and evaluates the technological choices available in detecting genetic variances in pharmacogenomics. Commonly used technologies such as sequencing, DNA array and chip technologies, mass spectrometry, gel- and chromatography-based technologies, as well as less commonly used methods are described in detail and illustrated with specific examples. Expert advice is presented on technological options to facilitate decisions about the utility and applicability of individual technologies for specific needs.
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Karl H. Hecker, PhD, is a staff scientist with PerkinElmer Corporation. His other book is "Genetic Variance Detection - the nuts & bolts of DHPLC in Genomics"..Review:
An essential contribution to the field of mutation discovery and genotyping. A reference guide for every molecular biology laboratory. --Norbert Arnold, Professor Dr. rer. nat.
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