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DNA-Encoded Chemical Libraries: Methods and Protocols (Methods in Molecular Biology, 2541) - Hardcover

 
9781071625446: DNA-Encoded Chemical Libraries: Methods and Protocols (Methods in Molecular Biology, 2541)
  • PublisherHumana
  • Publication date2022
  • ISBN 10 1071625446
  • ISBN 13 9781071625446
  • BindingHardcover
  • LanguageEnglish
  • Edition number1
  • Number of pages236
  • EditorIsrael David, Ding Yun

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9781071625477: DNA-Encoded Chemical Libraries: Methods and Protocols (Methods in Molecular Biology)

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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using . Seller Inventory # 577693056

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Yun Ding
Published by Springer US Sep 2022, 2022
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysis; computational methods used to analyze selections and choose compounds for resynthesis; and analysis of hit compounds. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, DNA-Encoded Chemical Libraries: Methods and Protocols is a valuable resource for scientists interested in DEL technology for drug discovery, and will contribute to the continued advancement in this important field. 236 pp. Englisch. Seller Inventory # 9781071625446

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Published by Springer US, 2022
ISBN 10: 1071625446 ISBN 13: 9781071625446
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysis; computational methods used to analyze selections and choose compounds for resynthesis; and analysis of hit compounds. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, DNA-Encoded Chemical Libraries:Methods and Protocols is a valuable resource for scientists interested in DEL technology for drug discovery, and will contribute to the continued advancement in this important field. Seller Inventory # 9781071625446

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