This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1896 Excerpt: ...was believed to prevent the blood from coagulating bv removing its tendency to form fibrin, and thus to favour a freer circulation, which would remove several of the injurious features of inflammatory fever. Small doses are now known not to have such an effect, while the larger doses will cause gastritis and other symptoms of poisoning. That derivatives may in a reflex manner affect local circulation, Brunton illustrates by a swollen finger, the painful vascular tension of which when held at the side is relieved by holding the finger above the bond. Dipping the finger in cold water, binding a cold compress upon the arm, or otherwise contracting, the arteries leading to the swelling, will lessen the tension of the vessels. A warm poultico on the finger will also give relief, the heat dilating the capillaries of the collateral circulation, thus diverting the blood current from the inflamed part. Cold, on the other hand, brings about a reflex contraction of the efferent arteries, so that las blood reaches the inflamed part. The fact that alterations similar to those caused by cold and heat in the finger may be produced on the circulation in internal organs in a reflex manner through the vaso-motor nervous system by derivatives may explain their na; as remedial measures. Because applications to the surface of the body affect nerves and vessels, and through them the nervous centres, the circulation, and the nutrition of the tissues, Bruce concludes that their action is very complex and still obscure. He holds that rubefacients and vesicants, by attracting blood and draining off plasma, will relieve the circulation of parts in immediate vascular connection with the area to which these derivatives are applied, while depressing to the same extent the general circul...
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