This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1920 Excerpt: ...figures were numerous in these cells. It is worthy of note that we find, farther out, in what we have termed the peripheral zone (even where the nerve tissue shows only slight damage) cells containing dye granules (Fig. 24). These are not associated with vessel walls or peri vascular spaces, and are undoubtedly neuroglia cells. Except for their dye content they cannot be distinguished from the neuroglia cells farther out in the brain substance. It was impossible to stain them so as to demonstrate their specific tinctorial reactions as neuroglia, and at the same time preserve their dye granules, since the small amount of blue dye contained in them is totally obscured by neuroglia stains. It was easy, however, to study the general morphology and at the same time inspect the dye content in sections lightly washed with carmin. Hematoxylin and eosin preparations were, of course, used for comparison. As one progressed nearer and nearer to the site of injury, more and more of these cells could be found, larger as they were encountered closer to the necrotic wall, until they finally occurred as free rounded or oval cells, lying in the intermediate zone. Their stimulation into phagocytic activity is probably due to their being situated in an area of inflammation. The amount of dye within these cells is so slight as to be quite insufficient of itself to account for even the meager amount of color that we find in the peripheral zone, in the gross specimens. This pale diffuse color, it will be remembered, is quite imperceptible in the sections, and is most apparent in the freshly fixed gross material. This vital staining reaction on the part of the neuroglia cells, and the occurrence of a series of transitional forms leading from the neuroglia of the peripheral zone to...
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