Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use.
Topics discussed include:
This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.
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Dr. Jose V. Bonilla’s career has been dedicated to the introduction and implementation of cutting-edge analytical technologies such as LC-MS, high-speed gas chromatography, high-speed GPC, online GC, online HPLC, and online near-IR. He has extensive experience in the management of industrial and pharmaceutical analytical laboratories in compliance with regulatory requirements and is the author and coauthor of several peer-reviewed publications.
Dr. G. Susan Srivatsa has more than 20 years of experience in the development of small molecules, proteins, peptides, and oligonucleotides as therapeutics. She has contributed to the successful development of more than 35 DNA and RNA oligonucleotide drug candidates through various stages of clinical development and has published widely in the area of oligonucleotide analysis in peer-reviewed journals.Review:
This is a unique resource for guiding the analysis of oligonucleotide-based drug products. No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use.
―Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes
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Book Description CRC Press, 2016. Paperback. Book Condition: NEW. 9781138198456 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE01214515
Book Description CRC Pr I Llc, 2016. Paperback. Book Condition: Brand New. 511 pages. 9.69x6.85 inches. In Stock. Bookseller Inventory # __1138198455
Book Description CRC Press, 2016. Paperback. Book Condition: New. Never used!. Bookseller Inventory # P111138198455