This book consists of articles from Wikia. Pages: 107. Chapters: Anesthetic drugs, Amobarbital, Chloroform, Hexobarbital, Ketamine, Local anesthetics, Nitrous oxide, Pentobarbital, Phencyclidine, Procaine, Propofol, Secobarbital, Succinylcholine, Tiletamine, Amobarbital, Apomorphine, Benzodiazepene, Benzodiazepines, Benzodiazepine withdrawal syndrome, Chloralose, Chlordiazepoxide, Clobazam, Clonazepam, Clorazepate, Codeine, Cyclopyrrolones, Diazepam, Diphenhydramine, Estazolam, Eszopiclone, Flunitrazepam, Flurazepam, Glutethimide, Hexobarbital, Hypnosedatives, Indiplon, Loprazolam, Lorazepam, Lormetazepam, Mebrobamate, Meprobamate, Methaqualone, Midazolam, Narcoanalysis, Narco Analysis, Nimetazepam, Nitrazepam, Oxazepam, Paraldehyde, Pentobarbital, Phenobarbital, Prazepam, Promethazine, Secobarbital, Temazepam, Thalidomide, Thiopental, Triazolam, Zaleplon, Zolpidem. Excerpt: Amobarbital (formerly known as amylobarbitone) is a drug that is a barbiturate derivative. It has sedative-hypnotic and analgesic properties. It is a white crystalline powder with no odor and a slightly bitter taste. If amobarbital is taken for extended periods of time, physical and psychological dependence can develop. According to an in vitro study conducted at the University of British Columbia, amobarbital works by activating GABAA receptors, which decreases input resistance, depresses burst and tonic firing, especially in ventrobasal and intralaminar neurons, while at the same time increasing burst duration and mean conductance at individual chloride channels; this increases both the amplitude and decay time of inhibitory postsynaptic currents. It has an LD50 in mice of 212 mg/kg s.c. Amobarbital undergoes both hydroxylation to form 3'-hydroxyamobarbital, which has both levorotatory and dextrorotatory isomers and N-glucosidation to form 1-(beta-D-glucopyranosyl)amobarbital. A vial of amytal sodium. The following drugs should be avoided when taking amobarbital: Amobarbital has been known...
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