Recombinant DNA Technology and Genetic Engineering

 
9781259006555: Recombinant DNA Technology and Genetic Engineering

Recombinant DNA (rDNA) is a form of artificial DNA that is created by combining two or more sequences that would not normally occur together through the gene splicing. It is created through the introduction of relevant DNA into an existing organism DNA, such as the plasmids of bacteria, to code for or alter different traits for a specific purpose, such as antibiotic. Recombinant DNA technology was made possible by the discovery, isolation and application of restriction endonucleases by Werner Arber, Daniel Nathans, and Hamilton Smith, for which they received the 1978 Nobel Prize in Medicine.

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About the Author:

"Dr K Rajagopal is currently working as Principal Scientist with the Institute of Microbial Technology (CSIR), Chandigarh. He obtained his BSc degree from Regional College of Education, Mysore (NCERT) and MSc degree from Central University, Hyderabad. In addition, Dr Rajagopal obtained his PhD from IMTECH, Chandigarh, and Postdoctoral degree from national Research Council (NRC), Ottawa, Canada. Among many outstanding achievements, his most significant contribution has been the recombinant clot-bursting enzyme, streptokinase, for the treatment of heart attacks. He is presently working on Probiotics research for the development of microbial strains as food supplements. Dr Rajagopal has several research publications in leading scientific journals to his credit. He was also bestowed with the prestigious of Canadian, German, and Korean Governments for carrying out researches at their laboratories. Over the years, he has been successful in popularising the field of science amongst school students and the present textbook is one of the steps in that direction."

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