Catalysis in Asymmetric Synthesis

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9781405175197: Catalysis in Asymmetric Synthesis
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Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists.

Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.

Topics covered include:

  • Reduction of alkenes, ketones and imines
  • Nucleophilic addition to carbonyl compounds
  • Catalytic carbon-carbon bond forming reactions
  • Catalytic reactions involving metal carbenoids
  • Conjugate addition reactions

Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.

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From the Back Cover:

Controlling the stereochemical outcome of reactions in the synthesis of complex natural products or bioactive materials represents a considerable intellectual and practical challenge for chemists. The stereochemical features of these products are usually essential to their bioactivity, so asymmetric synthesis has become a dominant feature of modern organic chemistry. Asymmetric catalysis is an important aspect of asymmetric synthesis, and one that has seen significant progress in the development of widely applicable methodology. This book is written from the point of view of the synthetic organic chemist, illustrating the transformations that can be achieved via this methodology, rather than the organometallic chemistry that lies behind. The emphasis is on non-enzymatic methods of asymmetric catalysis, although key references to enzyme-catalysed reactions have been incorporated where appropriate.

The book is extensively referenced and therefore provides a convenient point of entry to the primary literature for both experienced synthetic organic chemists and advanced students alike.

About the Author:

Dr Vittorio Caprio is Lecturer in Organic and Medicinal Chemistry in the Department of Chemistry, University of Auckland, Auckland, New Zealand

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Book Description John Wiley and Sons Ltd, United Kingdom, 2009. Paperback. Condition: New. 2nd Revised edition. Language: English . Brand New Book. Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.Topics covered include:* Reduction of alkenes, ketones and imines* Nucleophilic addition to carbonyl compounds* Catalytic carbon-carbon bond forming reactions* Catalytic reactions involving metal carbenoids* Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist. Seller Inventory # AAH9781405175197

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Book Description John Wiley and Sons Ltd, United Kingdom, 2009. Paperback. Condition: New. 2nd Revised edition. Language: English . Brand New Book. Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.Topics covered include:* Reduction of alkenes, ketones and imines* Nucleophilic addition to carbonyl compounds* Catalytic carbon-carbon bond forming reactions* Catalytic reactions involving metal carbenoids* Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist. Seller Inventory # AAH9781405175197

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