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Transport phenomena induced by micrometer size drops and bubbles are aesthetic, scientifically challenging, and play an important role in applications with relevance to the 21st century such as healthcare and energy efficiency. This book first describes an invention of a novel technique for generating drops and bubbles on demand in a microfluidic chip. The technique involves a PDMS chip with one or several microliter-size chambers driven by piezoelectric actuations. Individual aqueous microdrops are dispensed from the chamber to a main transport channel filled with an immiscible fluid. The drop formation process is characterized with respect to critical dispense parameters such as the shape and duration of the driving pulse. Several features of this drop on demand technique with direct relevance to lab on a chip applications are presented and discussed, such as the ability to merge drops of different reagents and the ability to encapsulate single cells. The next part of this book shows the study on the dynamics of gas-liquid interfaces, bounded by micro-geometric features such as the channel walls of a microfluidic chip. The efficiency of three different micro-geometries at anchoring the interface is compared. The effects of ultrasound on the interface are also investigated. The sonicated interface exhibits harmonic traveling waves or standing waves, the latter corresponding to a higher ultrasound level. Standing capillary waves with subharmonic and superharmonic frequencies are also observed, and are explained in the framework of parametric resonance theory, using the Mathieu equation. In the end, a very efficient gas-liquid separation method using an integrated hydrophobic porous membrane is demonstrated and explained. Bubbles generated at a T-junction are transported towards the gas removal section, where they slide along a hydrophobic membrane until complete removal. This efficient gas removal process occurs provided four criteria are simultaneously respected.
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Dr. Jie Xu is now an assistant professor at Washington State University Vancouver. He received both Master degree (2006) and PhD degree (2010) from Columbia University, and Bachelor degree from Tsinghua University with distinction (2005). His research interests are in micro interfacial sciences and micro/nano systems for health, energy and environmental applications. Jie has authored more than 20 journal and conference publications, one of which titled "Drop on demand in a microfluidic chip" is highly cited and has been highlighted by the Journal of Micromechanics and Microengineering for its "novelty, significance and potential impact on future research." Jie sits on the editorial board of the Columbia Undergraduate Science Journal, and he has been reviewing for the Journal of Micromechanics and Microengineering, Microfluidics and Nanofluidics, Measurement Science and Technology and the ASME congresses. Jie is the recipient of the Chinese Government Award for outstanding students, evaluated worldwide. He received January 2010 a research award from Sigma Xi Grants-in-Aid program to develop next generation microfluidic cell manipulation systems. He is a full member of Sigma Xi, The Scientific Research Society and a member of ASME, AAAS and IEEE.
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Book Description CreateSpace, 2010. Condition: New. book. Seller Inventory # M1453702709
Book Description CreateSpace, 2010. Paperback. Condition: New. Never used!. Seller Inventory # P111453702709