This book focuses, for the main part, on the HLA-B27 molecule, but its involvement in a clinical context is also covered in detail. This monograph is comprehensive, giving a general introduction as well as up to date information on the structure, immunological function and clinical relevance of the HLA-B27 molecule, especially with respect to Ankylosing Spondylitis and related Spondyloarthropathies. The rational design of future potential peptide tools for the selective immunotherapy of the disease is also discussed.
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