Pathophysiology of Heat Stroke (Colloquium Series on Integrated Systems Physiology: From Mol)

0 avg rating
( 0 ratings by Goodreads )
 
9781615046829: Pathophysiology of Heat Stroke (Colloquium Series on Integrated Systems Physiology: From Mol)
View all copies of this ISBN edition:
 
 

This book outlines current research efforts that are focused on identifying better diagnostic and prognostic biomarkers of organ injury due to heat illnesses such as heat exhaustion, heat injury, and heat stroke. The purpose of the research is to identify more effective biomarkers of organ damage that will facilitate better understanding of the pathophysiological changes occurring during recovery. Identification of more sensitive and specific diagnostics which are needed for identification of pharmacologic strategies that will improve recovery. Classic heat stroke is a life-threatening condition experienced primarily by the very young or elderly during annual heat waves and also by young, fit individuals during strenuous physical activity in hot or temperate environments. Heat stroke can result in central nervous system dysfunction that includes combativeness, delirium, seizures, and severe organ injury. Many heat stroke victims experience permanent neurological dysfunction and peripheral organ injury that require months or years to resolve. Heat stroke sequelae are a consequence of heat injury to the tissues in combination with coagulopathies and a systemic inflammatory response syndrome (SIRS). Endotoxin leakage across ischemic-damaged gut membranes is thought to initiate the SIRS with cytokines, and other inflammatory mediators are involved in this multi-factorial process. Rapid cooling at the time of heat stroke collapse is the most effective treatment to limit the severity of organ injury, but does not prevent long-term sequelae in all individuals. This book seeks to identify the current strategies that will improve recovery.

"synopsis" may belong to another edition of this title.

About the Author:

Lisa R. Leon, Ph.D., received a B.A. degree (1985) in Anthropology-Zoology, an M.S. in Kinesiology (1990) and Ph.D. (1996) in Physiology from the University of Michigan. She completed postdoctoral training at the Lovelace Institutes, the National Institutes of Health, and the University of Delaware before accepting a Research Physiologist position at the U.S. Army Research Institute of Environmental Medicine (USARIEM) in 2001. She is currently Team Leader of the Environmental Pathophysiology research program at USARIEM and also serves as Adjunct Associate Professor in the Human Physiology Program at Boston University. She is a member of several editorial boards including the Journal of Applied Physiology and the American Journal of Physiology. Her research is focused on unraveling the mechanisms that mediate systemic inflammation to heat stroke with the goal of discovering novel biomarkers and pharmacologics to improve diagnosis and treatment of multi-organ system dysfunction.

"About this title" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

Leon, Lisa R.
Published by Morgan and Claypool Publishers (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Quantity Available: > 20
Print on Demand
Seller:
Pbshop
(Wood Dale, IL, U.S.A.)
Rating
[?]

Book Description Morgan and Claypool Publishers, 2015. PAP. Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9781615046829

More information about this seller | Contact this seller

Buy New
US$ 39.48
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds

2.

Lisa R. Leon
Published by Morgan Claypool Publishers, United States (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: 10
Seller:
Book Depository hard to find
(London, United Kingdom)
Rating
[?]

Book Description Morgan Claypool Publishers, United States, 2015. Paperback. Condition: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Heat illnesses exist along a continuum starting with the mild condition of heat exhaustion and progressing to heat injury and heat stroke. Heat stroke is a life-threatening condition clinically characterized by a severe elevation in body temperature with central nervous system dysfunction that often includes combativeness, delirium, seizures, and coma. Classic heat stroke is experienced primarily by the very young or elderly during annual heat waves. Exertional heat stroke is a condition experienced by young, fit individuals during strenuous physical activity in hot or temperate environments. Heat stroke sequelae are a consequence of heat injury to the tissues in combination with coagulopathies and a systemic inflammatory response syndrome (SIRS) that often culminates in multi-organ system dysfunction or death. Endotoxin leakage across ischemic-damaged gut membranes is thought to initiate the SIRS with cytokines and other inflammatory mediators involved in this multi-factorial process. Rapid cooling at the time of heat stroke collapse is the most effective treatment to limit the severity of organ injury, but does not prevent long-term sequelae in all individuals. Unfortunately, there is limited understanding of the mechanisms mediating downstream effects of the SIRS on multi-organ injury and there are no clinical treatments to ensure recovery. Rather, many heat stroke victims experience permanent neurological dysfunction and peripheral organ injury that require months or years to resolve. Current research efforts are focused on identifying better diagnostic and prognostic biomarkers of organ injury for development of more effective pharmacologic strategies to improve recovery. Seller Inventory # TNP9781615046829

More information about this seller | Contact this seller

Buy New
US$ 48.28
Convert currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, rates & speeds

3.

Leon, Lisa R.
Published by Morgan & Claypool 5/1/2015 (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback or Softback Quantity Available: 10
Seller:
BargainBookStores
(Grand Rapids, MI, U.S.A.)
Rating
[?]

Book Description Morgan & Claypool 5/1/2015, 2015. Paperback or Softback. Condition: New. Pathophysiology of Heat Stroke. Book. Seller Inventory # BBS-9781615046829

More information about this seller | Contact this seller

Buy New
US$ 51.77
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

4.

Leon, Lisa R.
Published by Morgan and Claypool Publishers (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Quantity Available: > 20
Print on Demand
Seller:
Books2Anywhere
(Fairford, GLOS, United Kingdom)
Rating
[?]

Book Description Morgan and Claypool Publishers, 2015. PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9781615046829

More information about this seller | Contact this seller

Buy New
US$ 40.35
Convert currency

Add to Basket

Shipping: US$ 11.45
From United Kingdom to U.S.A.
Destination, rates & speeds

5.

Lisa R. Leon
Published by Morgan Claypool Publishers, United States (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: 10
Print on Demand
Seller:
Book Depository International
(London, United Kingdom)
Rating
[?]

Book Description Morgan Claypool Publishers, United States, 2015. Paperback. Condition: New. Language: English . Brand New Book ***** Print on Demand *****. Heat illnesses exist along a continuum starting with the mild condition of heat exhaustion and progressing to heat injury and heat stroke. Heat stroke is a life-threatening condition clinically characterized by a severe elevation in body temperature with central nervous system dysfunction that often includes combativeness, delirium, seizures, and coma. Classic heat stroke is experienced primarily by the very young or elderly during annual heat waves. Exertional heat stroke is a condition experienced by young, fit individuals during strenuous physical activity in hot or temperate environments. Heat stroke sequelae are a consequence of heat injury to the tissues in combination with coagulopathies and a systemic inflammatory response syndrome (SIRS) that often culminates in multi-organ system dysfunction or death. Endotoxin leakage across ischemic-damaged gut membranes is thought to initiate the SIRS with cytokines and other inflammatory mediators involved in this multi-factorial process. Rapid cooling at the time of heat stroke collapse is the most effective treatment to limit the severity of organ injury, but does not prevent long-term sequelae in all individuals. Unfortunately, there is limited understanding of the mechanisms mediating downstream effects of the SIRS on multi-organ injury and there are no clinical treatments to ensure recovery. Rather, many heat stroke victims experience permanent neurological dysfunction and peripheral organ injury that require months or years to resolve. Current research efforts are focused on identifying better diagnostic and prognostic biomarkers of organ injury for development of more effective pharmacologic strategies to improve recovery. Seller Inventory # APC9781615046829

More information about this seller | Contact this seller

Buy New
US$ 52.07
Convert currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, rates & speeds

6.

Lisa R. Leon
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Quantity Available: 5
Seller:
ReadWhiz
(Portland, OR, U.S.A.)
Rating
[?]

Book Description Condition: New. Seller Inventory # ria9781615046829_ing

More information about this seller | Contact this seller

Buy New
US$ 52.39
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

7.

Lisa R. Leon
Published by Morgan Claypool Publishers, United States (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: 10
Print on Demand
Seller:
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Morgan Claypool Publishers, United States, 2015. Paperback. Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Heat illnesses exist along a continuum starting with the mild condition of heat exhaustion and progressing to heat injury and heat stroke. Heat stroke is a life-threatening condition clinically characterized by a severe elevation in body temperature with central nervous system dysfunction that often includes combativeness, delirium, seizures, and coma. Classic heat stroke is experienced primarily by the very young or elderly during annual heat waves. Exertional heat stroke is a condition experienced by young, fit individuals during strenuous physical activity in hot or temperate environments. Heat stroke sequelae are a consequence of heat injury to the tissues in combination with coagulopathies and a systemic inflammatory response syndrome (SIRS) that often culminates in multi-organ system dysfunction or death. Endotoxin leakage across ischemic-damaged gut membranes is thought to initiate the SIRS with cytokines and other inflammatory mediators involved in this multi-factorial process. Rapid cooling at the time of heat stroke collapse is the most effective treatment to limit the severity of organ injury, but does not prevent long-term sequelae in all individuals. Unfortunately, there is limited understanding of the mechanisms mediating downstream effects of the SIRS on multi-organ injury and there are no clinical treatments to ensure recovery. Rather, many heat stroke victims experience permanent neurological dysfunction and peripheral organ injury that require months or years to resolve. Current research efforts are focused on identifying better diagnostic and prognostic biomarkers of organ injury for development of more effective pharmacologic strategies to improve recovery. Seller Inventory # APC9781615046829

More information about this seller | Contact this seller

Buy New
US$ 53.40
Convert currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, rates & speeds

8.

Leon, Lisa R.
Published by Biota Publishing (2016)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: 1
Print on Demand
Seller:
Ria Christie Collections
(Uxbridge, United Kingdom)
Rating
[?]

Book Description Biota Publishing, 2016. Paperback. Condition: New. PRINT ON DEMAND Book; New; Publication Year 2016; Not Signed; Fast Shipping from the UK. No. book. Seller Inventory # ria9781615046829_lsuk

More information about this seller | Contact this seller

Buy New
US$ 53.38
Convert currency

Add to Basket

Shipping: US$ 4.92
From United Kingdom to U.S.A.
Destination, rates & speeds

9.

Lisa R. Leon
Published by Biota Publishing
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: > 20
Seller:
BuySomeBooks
(Las Vegas, NV, U.S.A.)
Rating
[?]

Book Description Biota Publishing. Paperback. Condition: New. 106 pages. Dimensions: 9.2in. x 7.5in. x 0.2in.Heat illnesses exist along a continuum starting with the mild condition of heat exhaustion and progressing to heat injury and heat stroke. Heat stroke is a life-threatening condition clinically characterized by a severe elevation in body temperature with central nervous system dysfunction that often includes combativeness, delirium, seizures, and coma. Classic heat stroke is experienced primarily by the very young or elderly during annual heat waves. Exertional heat stroke is a condition experienced by young, fit individuals during strenuous physical activity in hot or temperate environments. Heat stroke sequelae are a consequence of heat injury to the tissues in combination with coagulopathies and a systemic inflammatory response syndrome (SIRS) that often culminates in multi-organ system dysfunction or death. Endotoxin leakage across ischemic-damaged gut membranes is thought to initiate the SIRS with cytokines and other inflammatory mediators involved in this multi-factorial process. Rapid cooling at the time of heat stroke collapse is the most effective treatment to limit the severity of organ injury, but does not prevent long-term sequelae in all individuals. Unfortunately, there is limited understanding of the mechanisms mediating downstream effects of the SIRS on multi-organ injury and there are no clinical treatments to ensure recovery. Rather, many heat stroke victims experience permanent neurological dysfunction and peripheral organ injury that require months or years to resolve. Current research efforts are focused on identifying better diagnostic and prognostic biomarkers of organ injury for development of more effective pharmacologic strategies to improve recovery. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Seller Inventory # 9781615046829

More information about this seller | Contact this seller

Buy New
US$ 60.27
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

10.

LEON
Published by Morgan & Claypool Publishers (2015)
ISBN 10: 1615046828 ISBN 13: 9781615046829
New Paperback Quantity Available: 1
Seller:
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Morgan & Claypool Publishers, 2015. Paperback. Condition: NEW. 9781615046829 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. For all enquiries, please contact Herb Tandree Philosophy Books directly - customer service is our primary goal. Seller Inventory # HTANDREE01043790

More information about this seller | Contact this seller

Buy New
US$ 56.99
Convert currency

Add to Basket

Shipping: US$ 10.17
From United Kingdom to U.S.A.
Destination, rates & speeds

There are more copies of this book

View all search results for this book