Inflammasomes have a seemingly simple architecture. A sensor molecule of the NLR or PYHIN protein family recruits the common adapter molecule apoptosis-associated speck-like protein containing a CARD (ASC). Even so, inflammasome activation is highly regulated at multiple steps and precise details of how inflammasomes are activated at the molecular level remain largely unknown. In The Inflammasome: Methods and Protocols, expert researchers in the field detail methods and protocols to study multiple aspects of inflammasome function. These methods include the generation of inflammasome stimuli, perturbance of cellular homeostasis, assessment of ASC speck formation, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, and analysis of inflammasome assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
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Inflammasomes have a seemingly simple architecture. A sensor molecule of the NLR or PYHIN protein family recruits the common adapter molecule apoptosis-associated speck-like protein containing a CARD (ASC). Even so, inflammasome activation is highly regulated at multiple steps and precise details of how inflammasomes are activated at the molecular level remain largely unknown. In The Inflammasome: Methods and Protocols, expert researchers in the field detail methods and protocols to study multiple aspects of inflammasome function. These methods include the generation of inflammasome stimuli, perturbance of cellular homeostasis, assessment of ASC speck formation, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, and analysis of inflammasome assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Presents current up-to-date methodologiesProvides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the expertsThis Methods in Molecular Biology book offers methods for studying. Seller Inventory # 4267649
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1beta cytokines, plus lab protocols, material lists and tips. 240 pp. Englisch. Seller Inventory # 9781627035224
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Buch. Condition: Neu. The Inflammasome | Methods and Protocols | Eicke Latz (u. a.) | Buch | xi | Englisch | 2013 | Humana | EAN 9781627035224 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Seller Inventory # 105979907
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Condition: New. This book details methods and protocols to study multiple aspects of inflammasome function. It features lists of necessary materials and reagents, step-by-step readily reproducible laboratory protocols and key tips on troubleshooting. Editor(s): De Nardo, Christine; Latz, Eicke. Series: Methods in Molecular Biology. Num Pages: 236 pages, 23 black & white illustrations, 21 colour illustrations, 5 black & white tables, biograph. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 20. Weight in Grams: 652. . 2013. Hardback. . . . . Seller Inventory # V9781627035224
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