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Although important advances have been made in treating epilepsy, we still await the miracle cure. Before looking forward we must look backward and this book provides that glimpse into the history of the development of treatment for epileptics. It brings together material from diverse sources to give a coherent narrative of the discovery and development of the drugs commonly used today.
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"This book describes the history of antiepileptic drug development and factors influencing the discovery process. The subject is covered in chronological order from the preantiepileptic drug era to the 1990s, and a review of several investigational antiepileptic agents is included. The purpose of the book is to provide a historical narrative of how antiepileptic drugs are discovered, with an emphasis on the role of chance, luck, and serendipity in the discovery process. The author also relates the historical development in antiepileptic drugs to advancements in other areas in the management of epilepsy. With recent advancements in neuropharmacology and the expected release of several new antiepileptic drugs in the next year, a book on this topic should be timely and valuable in providing a historical perspective from which to evaluate these new advances. Although the presentation is occasionally obscured by the lack of cohesiveness among topics, the author succeeds in providing a good overview of the subject.The book is written for physicians and other health professionals who care for the patient with epilepsy, pharmacologists, and medical historians. Although this work will be of general interest to the intended audience, the superficial coverage of the subject will require those seeking detailed information to refer to other sources that cover this topic in greater detail. The illustrations are of good quality, sufficient quantity, and complement the historical material discussed in the text. Appropriate references are provided throughout the text. The comprehensive list of citations at the end of each chapter will be valuable to those readers who wish to delve more deeply intothissubject. A major disappointment is the author's discussion of current concepts of antiepileptic drug therapy and neuropharmacology. The information presented in this section is outdated and in many instances misleading. Overall, however, I believe this is an informative text that provides an interesting perspective on how the current antiepileptic drugs were discovered. Of particular note, the chapter on Hauptmann's initial clinical studies with phenobarbital is excellent and should be required reading for any investigators working in this area." - James H. Fischer, PharmD, University of Illinois at Chicago College of Pharmacy Promo Copy
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Book Description CRC Press, 1993. Hardcover. Condition: Very Good. Dust Jacket Condition: Includes dust jacket. Book and jacket both in Very Good condition. Binding tight, pages clean and intact. DISPATCHED FROM THE UK WITHIN 24 HOURS ( BOOKS ORDERED OVER THE WEEKEND DISPATCHED ON MONDAY) BY ROYAL MAIL. ALL OVERSEAS ORDERS SENT BY AIR MAIL. Seller Inventory # mon0000532794
Book Description Parthenon Publishing Group, 1993. Hardcover. Condition: Very Good. Dust Jacket Condition: Very Good. First Edition. Publisher's hardback in very good condition: firm, square and tight with no snags or splits, just a trifle rubbed. Complete with original dustjacket: in decent shape, just slightly rubbed and moderately edge-worn. Contents sound and clean; no pen-marks. Not from a library so no such stamps or labels. Thus a tidy book in presentable condition. Seller Inventory # 084886